Q0BTT2 (MURI_GRABC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	GbCGDNIH1_0872

Organism

Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) [Complete proteome] [HAMAP]

Taxonomic identifier

391165 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Granulibacter

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	Glutamate racemase HAMAP MF_00258		PRO_1000078559

Sequences

	Sequence		Length	Mass (Da)
	Q0BTT2 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 992515F9D3E73042	FASTA	276	29,248
	10 20 30 40 50 60 MRKTDAHILV FDSGIGGLGV ADCIRRMLPA ATLGYVADTA GFPYGAMSDE ALVTRVLTVL 70 80 90 100 110 120 EQAIARLRPD MVVIACNTAS TLALSALRSR HDLPFIGCVP PLKWAASVSA TRQIGLLATP 130 140 150 160 170 180 ATVDRPYLTA LMQEHGQGCT LHAHGARHLA GYAEAVFRGE TVLVEAVRAE LGILGMIPDI 190 200 210 220 230 240 DAVALGCTHY GRLLPWLRQA MPRPVAWLDP AEAVARQAAR IAITAAATAA PDSLPRAAPC 250 260 270 WAQTVFTTGA VPDEATRQAW AAEGFPEWQP LEIASA

References

[1]

"Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis." Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E., Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M. J. Bacteriol. 189:8727-8736(2007) [PubMed: 17827295] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1260 / CGDNIH1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000394 Genomic DNA. Translation: ABI61770.1.
RefSeq	YP_744693.1. NC_008343.1.
3D structure databases
ProteinModelPortal	Q0BTT2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0BTT2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4275686.
GenomeReviews	Gene locus GbCGDNIH1_0872 in contig CP000394_GR.
KEGG	gbe:GbCGDNIH1_0872.
NMPDR	fig|391165.8.peg.875.
PATRIC	22077857. VBIGraBet83793_0910.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0796.
HOGENOM	HBG645102.
OMA	GCTHYLH.
PhylomeDB	Q0BTT2.
Enzyme and pathway databases
BioCyc	GBET391165:GBCGDNIH1_0872-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_GRABC

Accession

Primary (citable) accession number: Q0BTT2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	October 17, 2006
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program