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Q0BTB0 (MQO_GRABC) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:GbCGDNIH1_1044
OrganismGranulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) [Complete proteome] [HAMAP]
Taxonomic identifier391165 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Granulibacter

Protein attributes

Sequence length498 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 498498Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_1000023804

Sequences

Sequence LengthMass (Da)Tools
Q0BTB0 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: BDF86DB8CE0FAEEE

FASTA49854,230
        10         20         30         40         50         60 
MTSSANLRPD IVLIGAGIMG ATFGTLLKEL NPSYSMMMFE RLSDCGQESS QSWNNAGTGH 

        70         80         90        100        110        120 
AANCELNYTP QRPDGTVEIT QALRVNTEFD LSRQLWSYLV TKGAIPDPQS FIHPCPHMSM 

       130        140        150        160        170        180 
VWGAENVAFL KARFQAMSAH HCYHGMEYTE DGAQIEKWAP LTMEGRDPAE PVAATRIITG 

       190        200        210        220        230        240 
TDVDYGSLTH LLVAHLKAQP DFDLHYNTEV EGLDREPDGR WRVTFKDVNS GERHSVSAGF 

       250        260        270        280        290        300 
VFIGAGGASI DLLQKSNIPE GKGYGGFPVS GIWLRCDVDA VTQRHHAKVY GKASSGSPPM 

       310        320        330        340        350        360 
SVPHLDTRVI DGKTSLLFGP YAGFSTKFLK HGSLTDLFGS ITLHNIGPLL DVGRHNIELT 

       370        380        390        400        410        420 
EYLIAQVLQT HHHQFEMLKA FFPNAKRADW KEAVAGQRVQ VIKPYPDGGG FLEFGTEIVP 

       430        440        450        460        470        480 
AADHSLVALL GASPGASTAA AIALEVLEAC FADRLTDDAW LPALKRIIPT YGIDLREDAE 

       490 
ACRASRAATA SVLNIDNI

« Hide

References

[1]"Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis."
Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E., Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M.
J. Bacteriol. 189:8727-8736(2007) [PubMed: 17827295] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1260 / CGDNIH1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000394 Genomic DNA. Translation: ABI61942.1.
RefSeqYP_744865.1. NC_008343.1.

3D structure databases

ProteinModelPortalQ0BTB0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0BTB0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4276597.
GenomeReviewsGene locus GbCGDNIH1_1044 in contig CP000394_GR.
KEGGgbe:GbCGDNIH1_1044.
NMPDRfig|391165.8.peg.1043.
PATRIC22078231. VBIGraBet83793_1090.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
HOGENOMHBG289663.
OMANTQFEVS.
PhylomeDBQ0BTB0.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycGBET391165:GBCGDNIH1_1044-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_GRABC
AccessionPrimary (citable) accession number: Q0BTB0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 17, 2006
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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