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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciGBET391165:G1G6T-1073-MONOMER
UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:GbCGDNIH1_1044
OrganismiGranulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Taxonomic identifieri391165 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGranulibacter
Proteomesi
  • UP000001963 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000238041 – 498Probable malate:quinone oxidoreductaseAdd BLAST498

Interactioni

Protein-protein interaction databases

STRINGi391165.GbCGDNIH1_1044

Structurei

3D structure databases

ProteinModelPortaliQ0BTB0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiPQHDMAL
OrthoDBiPOG091H0B7C

Family and domain databases

HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

Q0BTB0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSANLRPD IVLIGAGIMG ATFGTLLKEL NPSYSMMMFE RLSDCGQESS
60 70 80 90 100
QSWNNAGTGH AANCELNYTP QRPDGTVEIT QALRVNTEFD LSRQLWSYLV
110 120 130 140 150
TKGAIPDPQS FIHPCPHMSM VWGAENVAFL KARFQAMSAH HCYHGMEYTE
160 170 180 190 200
DGAQIEKWAP LTMEGRDPAE PVAATRIITG TDVDYGSLTH LLVAHLKAQP
210 220 230 240 250
DFDLHYNTEV EGLDREPDGR WRVTFKDVNS GERHSVSAGF VFIGAGGASI
260 270 280 290 300
DLLQKSNIPE GKGYGGFPVS GIWLRCDVDA VTQRHHAKVY GKASSGSPPM
310 320 330 340 350
SVPHLDTRVI DGKTSLLFGP YAGFSTKFLK HGSLTDLFGS ITLHNIGPLL
360 370 380 390 400
DVGRHNIELT EYLIAQVLQT HHHQFEMLKA FFPNAKRADW KEAVAGQRVQ
410 420 430 440 450
VIKPYPDGGG FLEFGTEIVP AADHSLVALL GASPGASTAA AIALEVLEAC
460 470 480 490
FADRLTDDAW LPALKRIIPT YGIDLREDAE ACRASRAATA SVLNIDNI
Length:498
Mass (Da):54,230
Last modified:October 17, 2006 - v1
Checksum:iBDF86DB8CE0FAEEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000394 Genomic DNA Translation: ABI61942.1
RefSeqiWP_011631751.1, NC_008343.2

Genome annotation databases

EnsemblBacteriaiABI61942; ABI61942; GbCGDNIH1_1044
GeneIDi31475749
KEGGigbe:GbCGDNIH1_1044

Similar proteinsi

Entry informationi

Entry nameiMQO_GRABC
AccessioniPrimary (citable) accession number: Q0BTB0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 17, 2006
Last modified: February 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health