Reviewed, UniProtKB/Swiss-Prot Q0BTB0 (MQO_GRABC)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	GbCGDNIH1_1044

Organism

Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) [Complete proteome] [HAMAP]

Taxonomic identifier

391165 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Granulibacter

Protein attributes

Sequence length	498 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 498	498	Probable malate:quinone oxidoreductase		PRO_1000023804

Sequences

	Sequence		Length	Mass (Da)
	Q0BTB0-1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: BDF86DB8CE0FAEEE	FASTA	498	54,230
	10 20 30 40 50 60 MTSSANLRPD IVLIGAGIMG ATFGTLLKEL NPSYSMMMFE RLSDCGQESS QSWNNAGTGH 70 80 90 100 110 120 AANCELNYTP QRPDGTVEIT QALRVNTEFD LSRQLWSYLV TKGAIPDPQS FIHPCPHMSM 130 140 150 160 170 180 VWGAENVAFL KARFQAMSAH HCYHGMEYTE DGAQIEKWAP LTMEGRDPAE PVAATRIITG 190 200 210 220 230 240 TDVDYGSLTH LLVAHLKAQP DFDLHYNTEV EGLDREPDGR WRVTFKDVNS GERHSVSAGF 250 260 270 280 290 300 VFIGAGGASI DLLQKSNIPE GKGYGGFPVS GIWLRCDVDA VTQRHHAKVY GKASSGSPPM 310 320 330 340 350 360 SVPHLDTRVI DGKTSLLFGP YAGFSTKFLK HGSLTDLFGS ITLHNIGPLL DVGRHNIELT 370 380 390 400 410 420 EYLIAQVLQT HHHQFEMLKA FFPNAKRADW KEAVAGQRVQ VIKPYPDGGG FLEFGTEIVP 430 440 450 460 470 480 AADHSLVALL GASPGASTAA AIALEVLEAC FADRLTDDAW LPALKRIIPT YGIDLREDAE 490 ACRASRAATA SVLNIDNI

References

[1]

"Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis." Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E., Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M. J. Bacteriol. 189:8727-8736(2007) [PubMed: 17827295] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000394 Genomic DNA. Translation: ABI61942.1.
RefSeq	YP_744865.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4276597.
GenomeReviews	Gene locus GbCGDNIH1_1044 in contig CP000394_GR.
KEGG	gbe:GbCGDNIH1_1044.
NMPDR	fig|391165.8.peg.1043.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0BTB0.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_GRABC

Accession

Primary (citable) accession number: Q0BTB0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 17, 2006
Last modified:	November 4, 2008
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)