Reviewed, UniProtKB/Swiss-Prot Q0BSF0 (PDXY_GRABC)

Names and origin

Protein names

Recommended name:
    Pyridoxamine kinase
      Short name=PM kinase
    EC=2.7.1.35

Gene names

Name:	pdxY
Ordered Locus Names:	GbCGDNIH1_1354

Organism

Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) [Complete proteome] [HAMAP]

Taxonomic identifier

391165 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Granulibacter

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine By similarity.
Catalytic activity	ATP + pyridoxal = ADP + pyridoxal 5'-phosphate. HAMAP MF_01639
Sequence similarities	Belongs to the pyridoxine kinase family.

Ontologies

Keywords
Ligand	ATP-binding Metal-binding Nucleotide-binding Zinc
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP pyridoxine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glucokinase activity Inferred from electronic annotation. Source: HAMAP pyridoxal kinase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 286	286	Pyridoxamine kinase HAMAP MF_01639		PRO_0000269811
Sites
	Binding site	8	1	Substrate By similarity
	Binding site	43	1	Substrate By similarity
	Binding site	223	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0BSF0-1 [UniParc]. Last modified January 9, 2007. Version 2. Checksum: 83674D0AC0B48A01	FASTA	286	30,628
	10 20 30 40 50 60 MNILSIQSWV CYGHVGNASA VFPLQLLGAE VWAVNTVQFS NHTGYGDWTG QVFGGDDIAA 70 80 90 100 110 120 LMKGIADRGV LPRCDAVLSG YMGSDAIGGA ILDAVASVRA ANPEALYCCD PVIGDTGRGI 130 140 150 160 170 180 FVRPGLPELF RDRAVPTANI LTPNQFELEW LTGHHCRTLA DARAAVKVLA ESMIRQGPRI 190 200 210 220 230 240 ILVTSLHVAE TPSGSLDMLV YENGRFYLLR TPLLPVSING AGDAIAALFL FHRLDTGDAR 250 260 270 280 QALEKAASSV YGLLKRTAEA GSMEILTVAA RQEFLTPSTC FYAQIC

References

[1]

"Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis." Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E., Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M. J. Bacteriol. 189:8727-8736(2007) [PubMed: 17827295] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000394 Genomic DNA. Translation: ABI62252.1. Different initiation.
RefSeq	YP_745175.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4275222.
GenomeReviews	Gene locus GbCGDNIH1_1354 in contig CP000394_GR.
KEGG	gbe:GbCGDNIH1_1354.
NMPDR	fig|391165.8.peg.1341.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0BSF0.
Family and domain databases
HAMAP	MF_01639. [Tree]
InterPro	IPR013749. HMP-P_kinase-1. IPR004625. PyrdxlP_synth_PyrdxlKinase. [Graphical view]
Pfam	PF08543. Phos_pyr_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00687. pyridox_kin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PDXY_GRABC

Accession

Primary (citable) accession number: Q0BSF0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	June 16, 2009
This is version 17 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)