Q0BQ42 (URE3_GRABC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease subunit gamma
EC=3.5.1.5

Alternative name(s):
Urea amidohydrolase subunit gamma

Gene names

Name:	ureA
Ordered Locus Names:	GbCGDNIH1_2162

Organism

Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) [Complete proteome] [HAMAP]

Taxonomic identifier

391165 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Granulibacter

Protein attributes

Sequence length	100 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Urea + H2O = CO2 + 2 NH3. HAMAP MF_00739
Pathway	Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP MF_00739
Subunit structure	Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00739.
Sequence similarities	Belongs to the urease gamma subunit family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	urea metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro urease activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 100	100	Urease subunit gamma HAMAP MF_00739		PRO_1000046327

Sequences

	Sequence		Length	Mass (Da)
	Q0BQ42 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: A73042EB4B71FBF9	FASTA	100	11,150
	10 20 30 40 50 60 MHLTPREKDK LLIAMAAQVA RRRLERGVKL NHPEAIALIT DFVVEGARDG RSVAELMRDG 70 80 90 100 GTVLTREQVM EGVPEMIHDV QVEATFPDGT KLVTVHNPIR

References

[1]

"Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis." Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E., Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M. J. Bacteriol. 189:8727-8736(2007) [PubMed: 17827295] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1260 / CGDNIH1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000394 Genomic DNA. Translation: ABI63060.1.
RefSeq	YP_745983.1. NC_008343.1.
3D structure databases
ProteinModelPortal	Q0BQ42.
SMR	Q0BQ42. Positions 1-99.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0BQ42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4276743.
GenomeReviews	Gene locus GbCGDNIH1_2162 in contig CP000394_GR.
KEGG	gbe:GbCGDNIH1_2162.
NMPDR	fig|391165.8.peg.2099.
PATRIC	22080589. VBIGraBet83793_2243.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0831.
HOGENOM	HBG286300.
OMA	HVITRDQ.
ProtClustDB	CLSK2780093.
Enzyme and pathway databases
BioCyc	GBET391165:GBCGDNIH1_2162-MONOMER.
Family and domain databases
HAMAP	MF_00739. Urease_gamma. [Tree]
InterPro	IPR002026. Urease_gamma/gamma-beta_su. IPR012010. Urease_gamma_su. [Graphical view]
Gene3D	G3DSA:3.30.280.10. Urease_gamma_reg. 1 hit.
KO	K01430.
Pfam	PF00547. Urease_gamma. 1 hit. [Graphical view]
PIRSF	PIRSF001223. Urease_gamma. 1 hit.
ProDom	PD002319. Urease_gamma_reg. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF54111. Urease_gamma_reg. 1 hit.
TIGRFAMs	TIGR00193. Urease_gam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

URE3_GRABC

Accession

Primary (citable) accession number: Q0BQ42

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 17, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program