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Q0BMY1 (Q0BMY1_FRATO) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Isocitrate dehydrogenase (NADP(+)) EMBL ABI82553.1
EC=1.1.1.42 EMBL ABI82553.1
Gene names
Ordered Locus Names:FTH_0588
OrganismFrancisella tularensis subsp. holarctica (strain OSU18) [Complete proteome] [HAMAP]
Taxonomic identifier393011 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella ›

Protein attributes

Sequence length747 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region139 – 1468Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3571Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5551Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5591Magnesium or manganese By similarity PIRSR PIRSR009407-3
Binding site1521Substrate By similarity PIRSR PIRSR009407-2
Binding site5541Substrate By similarity PIRSR PIRSR009407-2
Site2621Critical for catalysis By similarity PIRSR PIRSR009407-1
Site4271Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence LengthMass (Da)Tools
Q0BMY1 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 0D2DB2BCA07C3F97

FASTA74783,584
        10         20         30         40         50         60 
MKFYLQEIFM HKIFYTFTDE APALATGSFL PIVESFTKVA DIELETKDIS LSARILANFN 

        70         80         90        100        110        120 
DYLTAEQKCS DDLAILRELA KTPDANIIKL PNISASIPQL TAAIKELQSK GYKIPDYPYE 

       130        140        150        160        170        180 
PKDDKEQEIK ARYAKVLGSA VNPVLREGNS DRRVADAVKK YAEKHPHSMG EWTKDSKSHV 

       190        200        210        220        230        240 
ASMSADDFYA NEKSYIVPKA TKVKIVHIDT KDTQTVLKDN LALEEKEIID ATKISIKALR 

       250        260        270        280        290        300 
EFYKNEIAKA KKEGTLLSLH LKATMMKVSD PILFGHAVEI FFEDIFKKYA KEFKELGVNP 

       310        320        330        340        350        360 
RNGWGDAVEK IKQLPQELQD KINADIEKVF AKQPDIAMVN SDKGITNLNV PSDVIIDASM 

       370        380        390        400        410        420 
PAAIRSSGKM WNKDGKLQDM KAMIPDRCYA GVYAATIDFC KENGAFDVAT MGDVSNVGLM 

       430        440        450        460        470        480 
AKKAEEYGSH DKTFEIQADG KVEVIDAEGN VIFEHQVEKG DIWRACQTKD IAVKDWVKLV 

       490        500        510        520        530        540 
VNRAKITQNP AIFWLDSKRA HDRNLIAKVN EYLTHHDTTG LDIQILSPVE ATKYSLKRMK 

       550        560        570        580        590        600 
EGKNTISVTG NVLRDYLTDL FPILELGTSA KMLSIVPLLA GGGLFETGAG GSAPKHVEQL 

       610        620        630        640        650        660 
IEENHLRWDS LGEFLALGAS LEDLAIKTRD AKIKVLAETL SQANKDFLDN DKSPRRKVGE 

       670        680        690        700        710        720 
LDTRGSHFYL AYYWVKALAE QTGNAELKAK FEPIYIELKA NKDKIVKELN DAQGKKVDVG 

       730        740 
GYYHMDKVKL DAVMRPSKTF NTILAQI

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References

[1]"Chromosome rearrangement and diversification of Francisella tularensis revealed by the type B (OSU18) genome sequence."
Petrosino J.F., Xiang Q., Karpathy S.E., Jiang H., Yerrapragada S., Liu Y., Gioia J., Hemphill L., Gonzalez A., Raghavan T.M., Uzman A., Fox G.E., Highlander S., Reichard M., Morton R.J., Clinkenbeard K.D., Weinstock G.M.
J. Bacteriol. 188:6977-6985(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OSU18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000437 Genomic DNA. Translation: ABI82553.1.
RefSeqYP_763190.1. NC_008369.1.

3D structure databases

ProteinModelPortalQ0BMY1.
SMRQ0BMY1. Positions 12-747.
ModBaseSearch...

Protein-protein interaction databases

STRING393011.FTH_0588.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI82553; ABI82553; FTH_0588.
GeneID4308091.
KEGGfth:FTH_0588.
PATRIC17951015. VBIFraTul3936_0659.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2838.
HOGENOMHOG000240860.
KOK00031.
OMAFRMCQTK.
ProtClustDBCLSK867411.

Enzyme and pathway databases

BioCycFTUL393011:GHFN-804-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ0BMY1_FRATO
AccessionPrimary (citable) accession number: Q0BMY1
Entry history
Integrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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