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Q0BKZ2 (G6PI_FRATO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:FTH_1430
OrganismFrancisella tularensis subsp. holarctica (strain OSU18) [Complete proteome] [HAMAP]
Taxonomic identifier393011 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 541541Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000013968

Sites

Active site3471Proton donor By similarity
Active site3781 By similarity
Active site5061 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0BKZ2 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: BE3D45512E9EF62D

FASTA54161,268
        10         20         30         40         50         60 
MLFCDDSKKY LKEQNINLKN EFDKDDKRVE KFSLKHQNIY FDYSKNLINN YILKSLLESA 

        70         80         90        100        110        120 
EKSSLKDKIK QMFNGAKINS TEHRAVLHTA LRDLSSTPLI VDGQDIRQEV TKEKQRVKEL 

       130        140        150        160        170        180 
VEKVVSGRWR GFSGKKITDI VNIGIGGSDL GPKMVVRALQ PYHCTDLKVH FVSNVDADSL 

       190        200        210        220        230        240 
LQALHVVDPE TTLFIIASKS FSTEETLLNS ISAREWLLDH YYEDEKAVAN HFVAISSKLD 

       250        260        270        280        290        300 
KVKEFGIDLE HCYKMWDWVG GRYSLWSSIG MSIAFAIGYD NFEKLLAGAY SVDKYFKETE 

       310        320        330        340        350        360 
FSKNIPVIMA LLASYYSCTY NSQSQALLPY DERLCYFVDY LQQADMESNG KSVNIAGGTV 

       370        380        390        400        410        420 
NYQTGVVLWG GVGTNGQHAF HQLLHQGNIF IPVDFIAIAT SHHNYDNHQQ ALLANCFAQS 

       430        440        450        460        470        480 
QALMFGQSYD MVYNELLKSG LNETQAKKLA AHKVIPGNRP STTILLDELS PYSLGALIAL 

       490        500        510        520        530        540 
YEHKIFVQGV LWDINSYDQW GVELGKKLGK NILKAMNDDS SDEYQNLDDS TRQLIAKVKN 


K 

« Hide

References

[1]"Chromosome rearrangement and diversification of Francisella tularensis revealed by the type B (OSU18) genome sequence."
Petrosino J.F., Xiang Q., Karpathy S.E., Jiang H., Yerrapragada S., Liu Y., Gioia J., Hemphill L., Gonzalez A., Raghavan T.M., Uzman A., Fox G.E., Highlander S., Reichard M., Morton R.J., Clinkenbeard K.D., Weinstock G.M.
J. Bacteriol. 188:6977-6985(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OSU18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000437 Genomic DNA. Translation: ABI83242.1.
RefSeqYP_763879.1. NC_008369.1.

3D structure databases

ProteinModelPortalQ0BKZ2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING393011.FTH_1430.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI83242; ABI83242; FTH_1430.
GeneID4307837.
KEGGfth:FTH_1430.
PATRIC17953034. VBIFraTul3936_1643.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycFTUL393011:GHFN-1465-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_FRATO
AccessionPrimary (citable) accession number: Q0BKZ2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 17, 2006
Last modified: June 11, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways