Q0BKA8 (Q0BKA8_FRATO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aconitate hydratase EMBL ABI83476.1
EC=4.2.1.3 EMBL ABI83476.1

Gene names

Name:	acnA EMBL ABI83476.1
Ordered Locus Names:	FTH_1708

Organism

Francisella tularensis subsp. holarctica (strain OSU18) [Complete proteome] [HAMAP]

Taxonomic identifier

393011 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella › Francisella tularensis › Francisella tularensis subsp. holarctica

Protein attributes

Sequence length	937 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Iron Iron-sulfur SAAS SAAS018136 Metal-binding
Molecular function	Lyase EMBL ABI83476.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: InterPro citrate hydro-lyase (cis-aconitate-forming) activity Inferred from electronic annotation. Source: EC isocitrate hydro-lyase (cis-aconitate-forming) activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0BKA8 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 3784B39F6F6980C9	FASTA	937	102,704
	10 20 30 40 50 60 MSDIKNITKL QIEDKGKKYS LYSLKKLSQE LGKDVTRLPY SIRVLLENQL RNIDGYKVKE 70 80 90 100 110 120 DDMHKVLDWD AKASSRPEIP HMPARVVMQD FTGVPAVVDL AAMRKAIKDA GGDADKINPL 130 140 150 160 170 180 VDTAMVIDHS VQVDFYGTKT ALAQNVAKEF ERNGERYSLL KWAQKAFDDF IVVPPGMGII 190 200 210 220 230 240 HQVNLEYLAK DALVKNINGE DVIYPDTLVG TDSHTTMING VGAVGWGVGG IEAEAVMLGQ 250 260 270 280 290 300 PYYMVLPDVV GVKFTGKLKT GVTATDLVLK VTEVLRKHGV VGKFVEYYGE GLESLSLPDR 310 320 330 340 350 360 ATIANMTPEY GATIGFFPVD EVTLDFFNNT NRSELVDAAR EMYKEQLLFR ENPAEEPEYS 370 380 390 400 410 420 NIVEIDLSEV ESNLAGPKRP QDRVAFHDMK KAFAEALVHE QGLHGFGLTD EQLQKSAEVK 430 440 450 460 470 480 GLNERITHGS VAIAAITSCT NTSNPSLLLG AGLLAKKANE KGLKVKPFVK TSLAPGSQVV 490 500 510 520 530 540 TQYLEKANLL PELENLGFNL VGYGCTTCIG NSGPLDEPVV EAINEADLIV ASVSSGNRNF 550 560 570 580 590 600 EGRINPHIKA NYLASPIHVV AYALAGTVDF DPVEDAIGKD AEGNDVYLAD IWPTTEEIAA 610 620 630 640 650 660 IQSHVINSDM FKKAYATVLD GTEEWQKLKA PEGKLYEFDS SSTYIQCPNF FEKFAEGNDD 670 680 690 700 710 720 LDIKGARTLL MLGDSVTTDH ISPAGAIPEE YPAGQYLKSH GVEKKDFNSY GSRRGNHEVM 730 740 750 760 770 780 MRGTFANIRI RNLLLDNVEG GFTKYHLDGS QQYVFDAAMK YKEKGIPLVI LAGKEYGTGS 790 800 810 820 830 840 SRDWAAKGTF LLGVKAVIAE SYERIHRSNL VGMGVLPLEY VNGQNAKTLG LDGTEMFNIK 850 860 870 880 890 900 NLNNIKPRQI VIVEAVHPKT AHTTTFEALA RLDADVDVDY LKNGGILQTV LKDIMGDKKE 910 920 930 SKSTQSTTSK GCGSADTSSE TSCPFAKIAN FFKKLFK

References

[1]

"Chromosome rearrangement and diversification of Francisella tularensis revealed by the type B (OSU18) genome sequence." Petrosino J.F., Xiang Q., Karpathy S.E., Jiang H., Yerrapragada S., Liu Y., Gioia J., Hemphill L., Gonzalez A., Raghavan T.M., Uzman A., Fox G.E., Highlander S., Reichard M., Morton R.J., Clinkenbeard K.D., Weinstock G.M. J. Bacteriol. 188:6977-6985(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OSU18.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000437 Genomic DNA. Translation: ABI83476.1.
RefSeq	YP_764113.1. NC_008369.1.
3D structure databases
ProteinModelPortal	Q0BKA8.
SMR	Q0BKA8. Positions 8-895.
ModBase	Search...
Protein-protein interaction databases
STRING	393011.FTH_1708.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABI83476; ABI83476; FTH_1708.
GeneID	4307447.
KEGG	fth:FTH_1708.
PATRIC	17953703. VBIFraTul3936_1968.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1048.
HOGENOM	HOG000025703.
KO	K01681.
OMA	YSKAQGM.
ProtClustDB	PRK09277.
Enzyme and pathway databases
BioCyc	FTUL393011:GHFN-1751-MONOMER.
Family and domain databases
Gene3D	3.20.19.10. 1 hit. 3.30.499.10. 2 hits. 3.40.1060.10. 1 hit.
InterPro	IPR015931. Acnase/IPM_dHydase_lsu_aba_1/3. IPR015937. Acoase/IPM_deHydtase. IPR001030. Acoase/IPM_deHydtase_lsu_aba. IPR015928. Aconitase/3IPM_dehydase_swvl. IPR006249. Aconitase/Fe_reg_prot_2. IPR015934. Aconitase/Fe_reg_prot_2/AcnD. IPR015932. Aconitase/IPMdHydase_lsu_aba_2. IPR018136. Aconitase_4Fe-4S_BS. IPR000573. AconitaseA/IPMdHydase_ssu_swvl. [Graphical view]
PANTHER	PTHR11670. PTHR11670. 1 hit. PTHR11670:SF1. PTHR11670:SF1. 1 hit.
Pfam	PF00330. Aconitase. 1 hit. PF00694. Aconitase_C. 1 hit. [Graphical view]
PRINTS	PR00415. ACONITASE.
SUPFAM	SSF52016. Aconitase/3IPM_dehydase_swvl. 1 hit. SSF53732. Aconitase_N. 1 hit.
TIGRFAMs	TIGR01341. aconitase_1. 1 hit.
PROSITE	PS00450. ACONITASE_1. 1 hit. PS01244. ACONITASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0BKA8_FRATO

Accession

Primary (citable) accession number: Q0BKA8

Entry history

Integrated into UniProtKB/TrEMBL:	October 17, 2006
Last sequence update:	October 17, 2006
Last modified:	May 29, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)