ID   TRPC_BURCM              Reviewed;         261 AA.
AC   Q0BIM8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Indole-3-glycerol phosphate synthase;
DE            Short=IGPS;
DE            EC=4.1.1.48;
GN   Name=trpC; OrderedLocusNames=Bamb_0436;
OS   Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia
OS   cepacia (strain AMMD)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=339670;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., Parke J., Coenye T.,
RA   Konstantinidis K., Ramette A., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia cepacia AMMD.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-
CC       phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC       tryptophan from chorismate: step 4/5.
CC   -!- SIMILARITY: Belongs to the trpC family.
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DR   EMBL; CP000440; ABI85995.1; -; Genomic_DNA.
DR   RefSeq; YP_772329.1; -.
DR   GeneID; 4309799; -.
DR   GenomeReviews; CP000440_GR; Bamb_0436.
DR   KEGG; bam:Bamb_0436; -.
DR   NMPDR; fig|339670.3.peg.5967; -.
DR   OMA; Q0BIM8; PLLCKDF.
DR   GO; GO:0004425; F:indole-3-glycerol-phosphate synthase activity; IEA:HAMAP.
DR   GO; GO:0000162; P:tryptophan biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00134; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR013798; Indole-3-glycerol_P_synth.
DR   InterPro; IPR001468; Indole-3-GPS_central.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   Pfam; PF00218; IGPS; 1.
DR   ProDom; PD001511; IGPS; 1.
DR   PROSITE; PS00614; IGPS; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; Decarboxylase; Lyase; Tryptophan biosynthesis.
FT   CHAIN         1    261       Indole-3-glycerol phosphate synthase.
FT                                /FTId=PRO_1000018453.
SQ   SEQUENCE   261 AA;  28551 MW;  405112891814A143 CRC64;
     MSDILDRIIA VKREEIAAAM RSAPLEALKL EASARDLRDF VGALRAKQAA GHAAVIAEVK
     KASPSKGVLR EHFVPADIAR SYAAHGAACL SVLTDEQFFQ GSVRYLEEAR AACTLPVLRK
     DFIVDAYQIL EARAMGADAI LLIAAALDTP LMQDLEAYAH SLGLAVLVEV HDRDEMEQAL
     TLKTPLLGIN NRNLRTFETS IQTTLDMLDM IPPERIVVTE SGILSRTDVD TMRAANVNAF
     LVGEAFMRAD QPGEELARMF F
//