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Q0BHY1 (Q0BHY1_BURCM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase 1 HAMAP MF_00051
Short name=SHMT 1 HAMAP MF_00051
Short name=Serine methylase 1 HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA1 HAMAP MF_00051
Ordered Locus Names:Bamb_0683
OrganismBurkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP]
Taxonomic identifier339670 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. RuleBase RU000585 HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. RuleBase RU000585 HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000585 HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU000585

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. RuleBase RU004104 HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2461N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
Q0BHY1 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: BCF2B8400B4EC5C1

FASTA43146,642
        10         20         30         40         50         60 
MYSAAPVNLY TLNGNRMFDR AQSTIANVDP ELFAAIEQEN RRQEDHIELI ASENYTSPAV 

        70         80         90        100        110        120 
MAAQGSQLTN KYAEGYPGKR YYGGCEYVDV VEQLAIDRVK QLFGAEAANV QPNSGSQANQ 

       130        140        150        160        170        180 
GVFFAMLKPG DTIMGMSLAH GGHLTHGSPV NMSGKWFNVV SYGLNEQEDI DYDAAEQLAQ 

       190        200        210        220        230        240 
EHKPKLIVAG ASAFALKIDF ERLAKIAKSV GAYLMVDMAH YAGLIAAGVY PNPVPHADFV 

       250        260        270        280        290        300 
TTTTHKSLRG PRGGVILMKS EYEKPINSAI FPGIQGGPLM HVIAAKAVAF KEALSPEFKA 

       310        320        330        340        350        360 
YQEKVVENAR VLAETLVKRG LRIVSGRTES HVMLVDLRAK NITGKAAEAA LGAAHITVNK 

       370        380        390        400        410        420 
NAIPNDPEKP FVTSGIRLGS PAMTTRGFGP AEAELVGNLI ADVLENPEDA ATIERVRTQV 

       430 
AELTKRFPVY R

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia cepacia AMMD."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000440 Genomic DNA. Translation: ABI86242.1.
RefSeqYP_772576.1. NC_008390.1.

3D structure databases

ProteinModelPortalQ0BHY1.
SMRQ0BHY1. Positions 20-430.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0BHY1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4308560.
GenomeReviewsGene locus Bamb_0683 in contig CP000440_GR.
KEGGbam:Bamb_0683.
NMPDRfig|339670.3.peg.3126.
PATRIC19016882. VBIBurAmb61564_0750.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0112.
HOGENOMHBG301263.
OMARIDFERI.
PhylomeDBQ0BHY1.
ProtClustDBPRK00011.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0BHY1_BURCM
AccessionPrimary (citable) accession number: Q0BHY1
Entry history
Integrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info