Q0BHS1 (Q0BHS1_BURCM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical HAMAP-Rule MF_00199
EC=3.6.1.41 HAMAP-Rule MF_00199

Alternative name(s):
Ap4A hydrolase HAMAP-Rule MF_00199
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase HAMAP-Rule MF_00199
Diadenosine tetraphosphatase HAMAP-Rule MF_00199

Gene names

Name:	apaH HAMAP-Rule MF_00199
Ordered Locus Names:	Bamb_0743 EMBL ABI86302.1

Organism

Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP] EMBL ABI86302.1

Taxonomic identifier

339670 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex › Burkholderia ambifaria

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP By similarity. HAMAP-Rule MF_00199 SAAS SAAS004617
Catalytic activity	P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP. HAMAP-Rule MF_00199 SAAS SAAS004617
Sequence similarities	Belongs to the Ap4A hydrolase family. HAMAP-Rule MF_00199

Ontologies

Keywords
Molecular function	Hydrolase HAMAP-Rule MF_00199 SAAS SAAS004617
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0BHS1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 0ECCDA04E4B38511	FASTA	279	30,567
	10 20 30 40 50 60 MLPRPIAIGD IQGCHSAFHS LLEKLSPPAD TPLWVAGDVV NRGPESLAAL RALVELGPRA 70 80 90 100 110 120 TVVLGNHDLH LLAVSAGIRT ERPGDTIGEI LDAPDADALL EWVRHRPFAH FEHGMLLVHA 130 140 150 160 170 180 GVLPQWDTSL ALELADELQR ALRAPDWRET LQSLYGNEPN QWSPNLKKRD RMRVAFNAFT 190 200 210 220 230 240 RLRFCTPDGA MDFKANGGPD SAPPGYLPWF DAPGRRTEDV TLVFGHWAAL GLMLRDNVVA 250 260 270 LDSGCVWGNQ LSAVRLTADP AQRTVTQVQC EACRTQGGE

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cepacia AMMD." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-244 / AMMD.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000440 Genomic DNA. Translation: ABI86302.1.
RefSeq	YP_772636.1. NC_008390.1.
3D structure databases
ProteinModelPortal	Q0BHS1.
ModBase	Search...
Protein-protein interaction databases
STRING	339670.Bamb_0743.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABI86302; ABI86302; Bamb_0743.
GeneID	4309302.
KEGG	bam:Bamb_0743.
PATRIC	19017006. VBIBurAmb61564_0812.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0639.
HOGENOM	HOG000251871.
KO	K01525.
OMA	WLRHQPL.
ProtClustDB	PRK00166.
Enzyme and pathway databases
BioCyc	BAMB339670:GH48-4202-MONOMER.
Family and domain databases
HAMAP	MF_00199. ApaH.
InterPro	IPR004617. ApaH. IPR004843. Metallo_PEstase_dom. [Graphical view]
Pfam	PF00149. Metallophos. 1 hit. [Graphical view]
PIRSF	PIRSF000903. B5n-ttraPtase_sm. 1 hit.
TIGRFAMs	TIGR00668. apaH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q0BHS1_BURCM

Accession

Primary (citable) accession number: Q0BHS1

Entry history

Integrated into UniProtKB/TrEMBL:	October 17, 2006
Last sequence update:	October 17, 2006
Last modified:	May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)