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Q0BG57 (IOLG_BURCM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Inositol 2-dehydrogenase

EC=1.1.1.18
Alternative name(s):
Myo-inositol 2-dehydrogenase
Short name=MI 2-dehydrogenase
Gene names
Name:iolG
Ordered Locus Names:Bamb_1308
OrganismBurkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP]
Taxonomic identifier339670 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex

Protein attributes

Sequence length337 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity. HAMAP-Rule MF_01671

Catalytic activity

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. HAMAP-Rule MF_01671

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01671

Sequence similarities

Belongs to the Gfo/Idh/MocA family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processinositol catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functioninositol 2-dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 337337Inositol 2-dehydrogenase HAMAP-Rule MF_01671
PRO_0000352558

Sequences

Sequence LengthMass (Da)Tools
Q0BG57 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 433489B8F8262409

FASTA33736,600
        10         20         30         40         50         60 
MTLQIGVIGC GAIGQDHIRR LTRTLSGARV VAVNDIDPQQ ARDAVTKYGL DAEIYGDGHE 

        70         80         90        100        110        120 
VVAAADVQAV LVTSWGPTHE AFVLDAIAHG KPVFCEKPLA VTAQGCMRIV EAEVAHGRRL 

       130        140        150        160        170        180 
VQVGFMRPYD EGYRALKHVI DSGEIGAPLM LHCAHRNQSV GERYTTDMAI TDTLIHELDV 

       190        200        210        220        230        240 
LRWLLGEDYT SAQVVYPKKT RHASAHLADP QIVLLETASG VRIDVEIFVN CQYGYDIQCE 

       250        260        270        280        290        300 
VVGENGIAKL PDPPAVGLKH AARRSVEIMT DWKERFIASY DVELQAFIDG VRQGALTGPS 

       310        320        330 
AWDGYAAAVA ADACVRAQQS GAVEPIAMAE RPAFYRG 

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia cepacia AMMD."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-244 / AMMD.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000440 Genomic DNA. Translation: ABI86866.1.
RefSeqYP_773200.1. NC_008390.1.

3D structure databases

ProteinModelPortalQ0BG57.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING339670.Bamb_1308.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI86866; ABI86866; Bamb_1308.
GeneID4309017.
KEGGbam:Bamb_1308.
PATRIC19018198. VBIBurAmb61564_1393.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0673.
HOGENOMHOG000227439.
KOK00010.
OMACFCEKPL.
OrthoDBEOG6GFGMS.

Enzyme and pathway databases

BioCycBAMB339670:GH48-1346-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_01671. IolG.
InterProIPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIOLG_BURCM
AccessionPrimary (citable) accession number: Q0BG57
Entry history
Integrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: October 17, 2006
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families