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Protein

Inositol 2-dehydrogenase

Gene

iolG

Organism
Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).UniRule annotation

Catalytic activityi

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol 2-dehydrogenaseUniRule annotation (EC:1.1.1.18UniRule annotation)
Alternative name(s):
Myo-inositol 2-dehydrogenaseUniRule annotation
Short name:
MI 2-dehydrogenaseUniRule annotation
Gene namesi
Name:iolGUniRule annotation
Ordered Locus Names:Bamb_1308
OrganismiBurkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD))
Taxonomic identifieri339670 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000000662 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003525581 – 337Inositol 2-dehydrogenaseAdd BLAST337

Proteomic databases

PRIDEiQ0BG57

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi339670.Bamb_1308

Structurei

3D structure databases

ProteinModelPortaliQ0BG57
SMRiQ0BG57
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Gfo/Idh/MocA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DRI Bacteria
COG0673 LUCA
HOGENOMiHOG000227439
KOiK00010
OMAiDHIRRCS
OrthoDBiPOG091H0FNG

Family and domain databases

HAMAPiMF_01671 IolG, 1 hit
InterProiView protein in InterPro
IPR023794 MI/DCI_dehydrogenase
IPR036291 NAD(P)-bd_dom_sf
IPR000683 Oxidoreductase_N
IPR004104 OxRdtase_C
PfamiView protein in Pfam
PF01408 GFO_IDH_MocA, 1 hit
PF02894 GFO_IDH_MocA_C, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

Q0BG57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLQIGVIGC GAIGQDHIRR LTRTLSGARV VAVNDIDPQQ ARDAVTKYGL
60 70 80 90 100
DAEIYGDGHE VVAAADVQAV LVTSWGPTHE AFVLDAIAHG KPVFCEKPLA
110 120 130 140 150
VTAQGCMRIV EAEVAHGRRL VQVGFMRPYD EGYRALKHVI DSGEIGAPLM
160 170 180 190 200
LHCAHRNQSV GERYTTDMAI TDTLIHELDV LRWLLGEDYT SAQVVYPKKT
210 220 230 240 250
RHASAHLADP QIVLLETASG VRIDVEIFVN CQYGYDIQCE VVGENGIAKL
260 270 280 290 300
PDPPAVGLKH AARRSVEIMT DWKERFIASY DVELQAFIDG VRQGALTGPS
310 320 330
AWDGYAAAVA ADACVRAQQS GAVEPIAMAE RPAFYRG
Length:337
Mass (Da):36,600
Last modified:October 17, 2006 - v1
Checksum:i433489B8F8262409
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000440 Genomic DNA Translation: ABI86866.1
RefSeqiWP_011656629.1, NZ_CP009798.1

Genome annotation databases

EnsemblBacteriaiABI86866; ABI86866; Bamb_1308
KEGGibam:Bamb_1308
PATRICifig|339670.21.peg.240

Similar proteinsi

Entry informationi

Entry nameiIOLG_BURCM
AccessioniPrimary (citable) accession number: Q0BG57
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: October 17, 2006
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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