Q0BDB7 (PSD_BURCM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

1. Phosphatidylserine decarboxylase alpha chain
2. Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	Bamb_2300

Organism

Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP]

Taxonomic identifier

339670 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	214 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664
Cofactor	Pyruvoyl group By similarity. HAMAP MF_00664
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphatidylethanolamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 181	181	Phosphatidylserine decarboxylase beta chain By similarity		PRO_1000026634
	Chain	182 – 214	33	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_1000026635
Sites
	Site	181 – 182	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	182	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0BDB7 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 8D93F4B1FB895B8C	FASTA	214	23,474
	10 20 30 40 50 60 MNYPHPIIAR EGWPFIAIAA VIALLIHAVG GFGFAWPFWL LLVFVVQFFR DPQRPIPAQP 70 80 90 100 110 120 NAVLCPADGR IVAVETTQDP YANREALKIS VFMNVFNVHS QRSPVDGAVT KVEYFPGAFL 130 140 150 160 170 180 NAAIDKASTE NERNALVIQT ASGKTVTAVQ IAGLVARRIL CYVRAGEPLS RGQRYGFIRF 190 200 210 GSRVDVYLPL GSRAKVSIGE KVYASSTILA ELEQ

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cepacia AMMD." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-244 / AMMD.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000440 Genomic DNA. Translation: ABI87856.1.
RefSeq	YP_774190.1. NC_008390.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0BDB7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4309097.
GenomeReviews	Gene locus Bamb_2300 in contig CP000440_GR.
KEGG	bam:Bamb_2300.
NMPDR	fig|339670.3.peg.5597.
PATRIC	19020272. VBIBurAmb61564_2403.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0688.
HOGENOM	HBG541103.
OMA	IFMSVFN.
ProtClustDB	PRK05305.
Enzyme and pathway databases
BioCyc	BAMB339670:BAMB_2300-MONOMER.
Family and domain databases
HAMAP	MF_00664. PS_decarb_type3. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR004428. PtdSer_deCO2ase-related. [Graphical view]
KO	K01613.
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00164. PS_decarb_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_BURCM

Accession

Primary (citable) accession number: Q0BDB7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 17, 2006
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program