ID   Q0BCV4_BURCM            Unreviewed;       479 AA.
AC   Q0BCV4;
DT   17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   17-OCT-2006, sequence version 1.
DT   27-MAR-2024, entry version 96.
DE   SubName: Full=Aldehyde dehydrogenase (NAD(+)) {ECO:0000313|EMBL:ABI88019.1};
DE            EC=1.2.1.3 {ECO:0000313|EMBL:ABI88019.1};
GN   OrderedLocusNames=Bamb_2463 {ECO:0000313|EMBL:ABI88019.1};
OS   Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia
OS   (strain AMMD)).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=339670 {ECO:0000313|EMBL:ABI88019.1, ECO:0000313|Proteomes:UP000000662};
RN   [1] {ECO:0000313|Proteomes:UP000000662}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-244 / AMMD {ECO:0000313|Proteomes:UP000000662};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K.,
RA   Ramette A., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia cepacia AMMD.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000440; ABI88019.1; -; Genomic_DNA.
DR   RefSeq; WP_011657634.1; NZ_CP009798.1.
DR   AlphaFoldDB; Q0BCV4; -.
DR   GeneID; 69543341; -.
DR   KEGG; bam:Bamb_2463; -.
DR   PATRIC; fig|339670.21.peg.2452; -.
DR   eggNOG; COG1012; Bacteria.
DR   Proteomes; UP000000662; Chromosome 1.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07109; ALDH_AAS00426; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003345,
KW   ECO:0000313|EMBL:ABI88019.1}.
FT   DOMAIN          12..474
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        248
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   479 AA;  50415 MW;  873383845A5183F5 CRC64;
     MEEAKHFIAG EWTLPAQLET IPVVDPSDGQ PFATIARGTA PDIERAVAAA REAFVGPWGA
     ASAAERGRVL MRLSARVADH LEELATIEAR DTGKPLKQAR ADAAALVRYF EFYAGAADKL
     HGETLPYQAG YTVLTVREPH GVTGHIVPWN YPMQIFGRSV GAALAAGNAC VVKPAEDACL
     SVLRVAELAA EAGLPAGALN IVTGYGHEAG AALARHPGID HISFTGSPAT GKLVTQMAAE
     NHVPVTLELG GKSPQIVFAD ADLEAALPVL VSAIVQNGGQ TCSAGSRVLI EHAVYEPLVD
     RLATAFNALR VGPSRADLDC GPLINAKQQQ RVWDFLSDAQ HDGIPMAGHG QVVADAPESG
     FYQAPALLRD VPASHRLAQE EVFGPVLAAM RFVDEEEAVA LANGTPYGLV AGIWTRDGAR
     QLRLARRLRA GQVFINNYGA GGGVELPFGG VGHSGHGREK GFEALYGFTA LKTIAIRHG
//