ID   GLPK_BURCM              Reviewed;         500 AA.
AC   Q0BC36;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=Glycerol kinase;
DE            EC=2.7.1.30;
DE   AltName: Full=ATP:glycerol 3-phosphotransferase;
DE   AltName: Full=Glycerokinase;
DE            Short=GK;
GN   Name=glpK; OrderedLocusNames=Bamb_2731;
OS   Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia
OS   cepacia (strain AMMD)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=339670;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., Parke J., Coenye T.,
RA   Konstantinidis K., Ramette A., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia cepacia AMMD.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key enzyme in the regulation of glycerol uptake and
CC       metabolism.
CC   -!- CATALYTIC ACTIVITY: ATP + glycerol = ADP + sn-glycerol 3-
CC       phosphate.
CC   -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol
CC       kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
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DR   EMBL; CP000440; ABI88287.1; -; Genomic_DNA.
DR   RefSeq; YP_774621.1; -.
DR   GeneID; 4310427; -.
DR   GenomeReviews; CP000440_GR; Bamb_2731.
DR   KEGG; bam:Bamb_2731; -.
DR   NMPDR; fig|339670.3.peg.434; -.
DR   OMA; Q0BC36; IAQREFT.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004370; F:glycerol kinase activity; IEA:HAMAP.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:HAMAP.
DR   HAMAP; MF_00186; -; 1.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR005999; Glycerol_kin.
DR   PANTHER; PTHR10196; FGGY_kin; 1.
DR   PANTHER; PTHR10196:SF9; Glycerol_kin; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   TIGRFAMs; TIGR01311; glycerol_kin; 1.
DR   PROSITE; PS00933; FGGY_KINASES_1; 1.
DR   PROSITE; PS00445; FGGY_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Glycerol metabolism; Kinase;
KW   Nucleotide-binding; Transferase.
FT   CHAIN         1    500       Glycerol kinase.
FT                                /FTId=PRO_1000020711.
FT   NP_BIND     410    414       ATP (By similarity).
FT   BINDING      13     13       Substrate (By similarity).
FT   BINDING      17     17       ATP (By similarity).
FT   BINDING      83     83       Substrate (By similarity).
FT   BINDING     135    135       Substrate (By similarity).
FT   BINDING     244    244       Substrate (By similarity).
FT   BINDING     266    266       ATP (By similarity).
FT   BINDING     309    309       ATP; via carbonyl oxygen (By similarity).
SQ   SEQUENCE   500 AA;  54649 MW;  A1FAF9258A2D3D54 CRC64;
     MQDQYILALD QGTTSSRAML FDRQGNIVSI AQKEFEQIYP QPGWVEHDPQ EIWSTQAGVA
     AEAVTRTGLN GTSIAAIGIT NQRETTIVWD RETGQPVYNA IVWQDRRTAD FCDSLKKQGL
     EAKVRAKTGL PIDSYFSATK IRWILDNVPG ARDKARQGKL AFGTVDSWLV WNFTKHELHV
     TDVTNASRTM LFNIHTREWD SELLELLDIP RSMLPDVKAS SEIYGHTKTT VFASKIPLAG
     IAGDQHAALF GQMCTTSGMV KNTYGTGCFL MMNTGDKPIE SKNNLVTTIA WQIGDDVQYA
     LEGSIFIAGA VVQWLRDGVG IIKTAAEIEA LAASVPHTDG VYLVPAFAGL GAPHWNARAR
     GSVFGVTRGT TSAHLARAAL DAIAYQSLDV LAAMEADSGI SIGELRVDGG ASANDLLMQF
     QADLLGVDAV RPQITETTAL GAAYLAGLAI GYWKNLDEVR SQWQLDRRFA PSMPKEQVEQ
     RMAGWQRAVR AAKAWADDTQ
//