Q0BBN1 (Q0BBN1_BURCM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Bamb_2886

Organism

Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP]

Taxonomic identifier

339670 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	1071 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0BBN1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 2DCE093989EB462A	FASTA	1,071	118,709
	10 20 30 40 50 60 MVAEFSWLPD YAELFCRSNF SFLHGASHAE ELVERAAELG YRGIAITDEC SLAGAPRMHV 70 80 90 100 110 120 AAKAQGLPLI VGSFFEVTPD EVTPGHDPGP GAFGLVLLAQ NREGYGNLSE LISWRRMASP 130 140 150 160 170 180 KGTYRLTSRM LSAPPAEFAH LRGMPDCFAI LVPTYPVRAD VLDAQVAWFR ATFGARARLG 190 200 210 220 230 240 LVQLQRPLDG AQREEIRAAG ERRGVRIVAL GDVTMHRRSC KPLQDVMTAI RVGMPVSECG 250 260 270 280 290 300 YALAPNAEQH LRARGRIAKL FSPEELDETC AILDACDFKL DSLQYEYPDE IVPKGLTPTR 310 320 330 340 350 360 HLEQETFAGA AARYPQGIPE KVERQIRYEL DLIARLSYEP FFLTVYDIVK YARSQNILCQ 370 380 390 400 410 420 GRGSAANSVV CYCLGITEVN PEQSTMLFER FISEERGEPP DIDVDFEHQR REEVIQHIYK 430 440 450 460 470 480 KYGHDRAALA AAVSTYRPRG VLRETGKALG VDPMLVDRVA KAHRWFDGSR DLLQQFASTG 490 500 510 520 530 540 LDPATPIIRA WAELAGRLLN FPRHLSQHSG GFVISRGKLT RLVPVENAAM DGRRVIQWDK 550 560 570 580 590 600 DDLEALGLMK VDVLALGMLS ALHRAFDLRT AWRGPQEDGQ PFTLKHIPQD DEATYDMICR 610 620 630 640 650 660 ADTVGVFQIE SRAQMSMLPR LKPRNYYDLV VEVSIVRPGP IQGGAVHPYL KRRRIQAGEE 670 680 690 700 710 720 EGEITYPSDA LRVVLERTLG VPIFQEQVMQ IAIVAAGFTP GEADRLRRAM AAWKRRGDLG 730 740 750 760 770 780 PYHDKIVNGM LERGYTREFA EQIFEQIKGF GEYGFPESHA ASFAKLAYAS SWLKCHEPAI 790 800 810 820 830 840 FLAALLNSQP MGFYPPSQLV QDAKRHGVQV LPIDVTLSNW EASLEALPDQ PPPHGQPAVR 850 860 870 880 890 900 LGLSLVRGLG EAAARRIEAA RAAGPFDNVD VLARRAQLER RDLEALAAAN ALVTLAGHRR 910 920 930 940 950 960 DALWQAVAAA PERDLLAAAP IDEPEKPALG APSEADDILA DYDTTGLTLN RHPVALLRPA 970 980 990 1000 1010 1020 LRAQRLSSAA ELRDRSDGRL ARACGIVTAR QMPGTAKGVM FMTLEDETGC VNVIVRPELL 1030 1040 1050 1060 1070 ARQRRETLDS RLLAVSGVWQ VVSDVRHLVA QHFEDLTPLL GGLRTSSREF H

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cepacia AMMD." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000440 Genomic DNA. Translation: ABI88442.1.
RefSeq	YP_774776.1. NC_008390.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0BBN1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4310735.
GenomeReviews	Gene locus Bamb_2886 in contig CP000440_GR.
KEGG	bam:Bamb_2886.
NMPDR	fig|339670.3.peg.278.
PATRIC	19021520. VBIBurAmb61564_3021.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	EQPAIRL.
ProtClustDB	PRK05672.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q0BBN1_BURCM

Accession

Primary (citable) accession number: Q0BBN1

Entry history

Integrated into UniProtKB/TrEMBL:	October 17, 2006
Last sequence update:	October 17, 2006
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)