Reviewed, UniProtKB/Swiss-Prot Q0BBE9 (SYR_BURCM)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	Bamb_2968

Organism

Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP]

Taxonomic identifier

339670 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	593 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 593	593	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_1000017999
Regions
	Motif	138 – 148	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q0BBE9-1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 5441A622104ACDCC	FASTA	593	64,289
	10 20 30 40 50 60 MLPAHKQTLE ALLADSVTQV AHALKGADAA FVAPAITLER PKVAAHGDVA CNVAMQLAKP 70 80 90 100 110 120 LGTNPRQLAE KIVAALTAQP AAQGLVDAAD IAGPGFINLR LTAAAKQAVI AAVFEQGRAF 130 140 150 160 170 180 GTSDREKGKQ VLLEFVSANP TGPLHVGHGR QAALGDVLAN VIASQGYAVH REFYYNDAGV 190 200 210 220 230 240 QIGNLAISTQ ARARGLKPGD AGWPEAAYNG EYIADIARDY LNRETVAAKD GEPVTGAGDI 250 260 270 280 290 300 DDLDAIRKFA VAYLRHEQDM DLQAFGVKFD QYYLESSLYS EGRVEKTVDA LVKAGMTYEQ 310 320 330 340 350 360 DGALWLRTTD EGDDKDRVMR KSDGTYTYFV PDVAYHVTKW ERGFTQVINI QGSDHHGTIA 370 380 390 400 410 420 RVRAGLQGLH VGIPKGYPDY VLHKMVTVMR DGQEVKLSKR AGSYVTVRDL IEWSGGAAPG 430 440 450 460 470 480 QEAAPDLIDE ATITRGRDAV RFFLISRKAD TEFVFDIDLA LKQNDENPVY YVQYAHARIC 490 500 510 520 530 540 SVLNELKSRY NVDVAQLPGA DLSQLTSAQA VSLMQKLAEY PDMLTHAAKE LAPHAVAFYL 550 560 570 580 590 RDLAGEFHSF YNAERVLVDD EAPRNARAAL LAATRQVLEN GLAVLGVSAP AKM

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cepacia AMMD." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000440 Genomic DNA. Translation: ABI88524.1.
RefSeq	YP_774858.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4310555.
GenomeReviews	Gene locus Bamb_2968 in contig CP000440_GR.
KEGG	bam:Bamb_2968.
NMPDR	fig|339670.3.peg.196.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	Q0BBE9. ADHHGYV.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BURCM

Accession

Primary (citable) accession number: Q0BBE9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 17, 2006
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)