ID   BIOD_BURCM              Reviewed;         239 AA.
AC   Q0BBD5;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 18.
DE   RecName: Full=Dethiobiotin synthetase;
DE            EC=6.3.3.3;
DE   AltName: Full=Dethiobiotin synthase;
DE   AltName: Full=DTB synthetase;
DE            Short=DTBS;
GN   Name=bioD; OrderedLocusNames=Bamb_2982;
OS   Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia
OS   cepacia (strain AMMD)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=339670;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., Parke J., Coenye T.,
RA   Konstantinidis K., Ramette A., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia cepacia AMMD.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + 7,8-diaminononanoate + CO(2) = ADP +
CC       phosphate + dethiobiotin.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- PATHWAY: Cofactor biosynthesis; biotin biosynthesis; biotin from
CC       6-carboxyhexanoyl-CoA: step 3/4.
CC   -!- SIMILARITY: Belongs to the dethiobiotin synthetase family.
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DR   EMBL; CP000440; ABI88538.1; -; Genomic_DNA.
DR   RefSeq; YP_774872.1; -.
DR   GeneID; 4310569; -.
DR   GenomeReviews; CP000440_GR; Bamb_2982.
DR   KEGG; bam:Bamb_2982; -.
DR   NMPDR; fig|339670.3.peg.182; -.
DR   OMA; Q0BBD5; YFEAPLA.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004141; F:dethiobiotin synthase activity; IEA:HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0009102; P:biotin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00336; -; 1.
DR   InterPro; IPR004472; BioD_synth.
DR   PIRSF; PIRSF006755; DTB_synth; 1.
DR   TIGRFAMs; TIGR00347; bioD; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Biotin biosynthesis; Complete proteome; Ligase;
KW   Magnesium; Nucleotide-binding.
FT   CHAIN         1    239       Dethiobiotin synthetase.
FT                                /FTId=PRO_0000302488.
FT   NP_BIND      11     19       ATP (By similarity).
SQ   SEQUENCE   239 AA;  25058 MW;  3234FCC0F017916C CRC64;
     MTAPLSLFVT GTDTEIGKTF VSAAMLHGFA RHGLRAAALK PVAAGAYERD GVWRNEDADQ
     LDAAANVVLP PELRTPFLLK APAAPHIVAA QEGVTLDIDT IVACHREALT RADVVVVEGV
     GGFRVPLTDT QDTADLAVAL GLPVVLVVGV RLGCISHALL TADAIRQRGL TLAGWVANHV
     DPAMSYADEN VATIRDWLAR EHGAPLLGRI PHMSPAAAES AAAMLDIAAL VETLRAAQH
//