ID   DAPF_BURCM              Reviewed;         289 AA.
AC   Q0BAY6;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=Diaminopimelate epimerase;
DE            Short=DAP epimerase;
DE            EC=5.1.1.7;
GN   Name=dapF; OrderedLocusNames=Bamb_3131;
OS   Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia
OS   cepacia (strain AMMD)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=339670;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., Parke J., Coenye T.,
RA   Konstantinidis K., Ramette A., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia cepacia AMMD.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: LL-2,6-diaminoheptanedioate = meso-
CC       diaminoheptanedioate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; DL-diaminopimelate from LL-diaminopimelate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the diaminopimelate epimerase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000440; ABI88687.1; -; Genomic_DNA.
DR   RefSeq; YP_775021.1; -.
DR   GeneID; 4310613; -.
DR   GenomeReviews; CP000440_GR; Bamb_3131.
DR   KEGG; bam:Bamb_3131; -.
DR   NMPDR; fig|339670.3.peg.35; -.
DR   OMA; Q0BAY6; PHAVLRV.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008837; F:diaminopimelate epimerase activity; IEA:HAMAP.
DR   GO; GO:0009089; P:lysine biosynthetic process via diaminopime...; IEA:HAMAP.
DR   HAMAP; MF_00197; -; 1.
DR   InterPro; IPR001653; DAP_epimerase.
DR   InterPro; IPR018510; DAP_epimerase_CS.
DR   Pfam; PF01678; DAP_epimerase; 2.
DR   TIGRFAMs; TIGR00652; DapF; 1.
DR   PROSITE; PS01326; DAP_EPIMERASE; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Lysine biosynthesis.
FT   CHAIN         1    289       Diaminopimelate epimerase.
FT                                /FTId=PRO_1000011853.
FT   ACT_SITE     76     76       By similarity.
FT   ACT_SITE    227    227       By similarity.
SQ   SEQUENCE   289 AA;  30854 MW;  AA542A2B345C3F1D CRC64;
     MKLSFTKMHG AGNDFVVLDG YSRALPPLTE AQVRALANRH FGIGADQLLL VEKPTVDGAD
     FKYRIFNCDG GEVEHCGNGA RCFVKFVSDR GLTDKRSVRV QVMKGLITLT LQDNGEVVVD
     MGAPVFAPAQ VPFDVSGLDG RAEGRDTLWP LDVGGATRWI SAVSMGNPHA VQVVDDVEAY
     PVLEEGPLIE RHARFPQRVN AGFMQIVSRH EVKLRVYERG AGETLACGTG ACAAVAAGIR
     RGLLDSPVTV HTHGGTLTIG WDGARDEAAA LMMAGPAATV FEGEIDLTA
//