Reviewed, UniProtKB/Swiss-Prot Q0BAY6 (DAPF_BURCM)

Names and origin

Protein names

Recommended name:
    Diaminopimelate epimerase
      Short name=DAP epimerase
    EC=5.1.1.7

Gene names

Name:	dapF
Ordered Locus Names:	Bamb_3131

Organism

Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP]

Taxonomic identifier

339670 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-diaminopimelate from LL-diaminopimelate: step 1/1. HAMAP MF_00197
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Lysine biosynthesis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	diaminopimelate epimerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 289	289	Diaminopimelate epimerase HAMAP MF_00197		PRO_1000011853
Sites
	Active site	76	1	By similarity
	Active site	227	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0BAY6-1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: AA542A2B345C3F1D	FASTA	289	30,854
	10 20 30 40 50 60 MKLSFTKMHG AGNDFVVLDG YSRALPPLTE AQVRALANRH FGIGADQLLL VEKPTVDGAD 70 80 90 100 110 120 FKYRIFNCDG GEVEHCGNGA RCFVKFVSDR GLTDKRSVRV QVMKGLITLT LQDNGEVVVD 130 140 150 160 170 180 MGAPVFAPAQ VPFDVSGLDG RAEGRDTLWP LDVGGATRWI SAVSMGNPHA VQVVDDVEAY 190 200 210 220 230 240 PVLEEGPLIE RHARFPQRVN AGFMQIVSRH EVKLRVYERG AGETLACGTG ACAAVAAGIR 250 260 270 280 RGLLDSPVTV HTHGGTLTIG WDGARDEAAA LMMAGPAATV FEGEIDLTA

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cepacia AMMD." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000440 Genomic DNA. Translation: ABI88687.1.
RefSeq	YP_775021.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4310613.
GenomeReviews	Gene locus Bamb_3131 in contig CP000440_GR.
KEGG	bam:Bamb_3131.
NMPDR	fig|339670.3.peg.35.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	Q0BAY6. PHAVLRV.
Family and domain databases
HAMAP	MF_00197. [Tree]
InterPro	IPR001653. DAP_epimerase. IPR018510. DAP_epimerase_CS. [Graphical view]
Pfam	PF01678. DAP_epimerase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00652. DapF. 1 hit.
PROSITE	PS01326. DAP_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DAPF_BURCM

Accession

Primary (citable) accession number: Q0BAY6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 17, 2006
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)