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Q0B874 (Q0B874_BURCM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:Bamb_4096
OrganismBurkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP] EMBL ABI89649.1
Taxonomic identifier339670 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2281 By similarity HAMAP MF_01265
Binding site1321NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1981NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
Q0B874 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 5D9D634ED794D206

FASTA27528,577
        10         20         30         40         50         60 
MRNGHAHGHA PVDVAMIGFG AIGAAVYHAV EHDASLRVAH VIVPAHQRDA VQRELGGAVE 

        70         80         90        100        110        120 
VVSSVDALAR RPEFALECAG HSALVDHVVP LLKAGTDCAV ASIGALSDLA LLDVLSQAAD 

       130        140        150        160        170        180 
EGDATLTLLS GAIGGIDALA SAKQGGLDEV LYVGRKPPLG WLGTPAEELC DLRAMTEEKV 

       190        200        210        220        230        240 
IFEGTARDAA RLYPKNANVA ATVALAGLGL DATRVRLIAD PAVTRNVHRI TARGAFGEMS 

       250        260        270 
LEMSGRPLPD NPKTSALTAY CAIRALRNRA ARCVI

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References

[1]"Complete sequence of chromosome 2 of Burkholderia cepacia AMMD."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000441 Genomic DNA. Translation: ABI89649.1.
RefSeqYP_775983.1. NC_008391.1.

3D structure databases

ProteinModelPortalQ0B874.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0B874.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4312991.
GenomeReviewsGene locus Bamb_4096 in contig CP000441_GR.
KEGGbam:Bamb_4096.
NMPDRfig|339670.3.peg.985.
PATRIC19024061. VBIBurAmb61564_4287.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1712.
HOGENOMHBG649642.
OMAECAGHSA.
ProtClustDBPRK13303.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ0B874_BURCM
AccessionPrimary (citable) accession number: Q0B874
Entry history
Integrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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