Reviewed, UniProtKB/Swiss-Prot Q0B5P1 (ADC_BURCM)

Names and origin

Protein names

Recommended name:
    Probable acetoacetate decarboxylase
      Short name=ADC
      Short name=AAD
    EC=4.1.1.4

Gene names

Name:	adc
Ordered Locus Names:	Bamb_4983

Organism

Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP]

Taxonomic identifier

339670 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	246 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide By similarity.
Catalytic activity	Acetoacetate = acetone + CO2. HAMAP MF_00597
Sequence similarities	Belongs to the ADC family.

Ontologies

Keywords
Ligand	Schiff base
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acetoacetate decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 246	246	Probable acetoacetate decarboxylase HAMAP MF_00597		PRO_1000025633
Sites
	Active site	116	1	Schiff-base intermediate with acetoacetate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0B5P1-1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: E406ADA8C8E2D88B	FASTA	246	27,413
	10 20 30 40 50 60 MKISDVRSKA FAMPLTSPAF PMGPYRFVDR EFLIITYRTD PDRLREIVPE PLQITEPLVH 70 80 90 100 110 120 YEFIRMADST GFGDYTESGQ VIPVEYNGQA GGYTLAMYLD DHPPIAGGRE LWGFPKKLAS 130 140 150 160 170 180 PTLHVNTDHI LGTLDYGKVR VATGTMGYKH KDLDIEEQAK RLAGPNFLLK IIPHVDGTAR 190 200 210 220 230 240 VCELVRYYMQ DIKMKGAWTG PASLELAPHA LAPVADLPVL EIVEARHIVA DLTLGLGEVV YDYLAQ

References

[1]

"Complete sequence of chromosome 2 of Burkholderia cepacia AMMD." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000441 Genomic DNA. Translation: ABI90532.1.
RefSeq	YP_776866.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4313874.
GenomeReviews	Gene locus Bamb_4983 in contig CP000441_GR.
KEGG	bam:Bamb_4983.
NMPDR	fig|339670.3.peg.1707.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	Q0B5P1. TATMGYK.
Family and domain databases
HAMAP	MF_00597. [Tree]
InterPro	IPR010451. Acetoacetate_decarboxylase. [Graphical view]
Pfam	PF06314. ADC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADC_BURCM

Accession

Primary (citable) accession number: Q0B5P1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 17, 2006
Last modified:	June 16, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)