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Q0B5L0 (Q0B5L0_BURCM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 HAMAP MF_00223
EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I HAMAP MF_00223
Gene names
Name:folE HAMAP MF_00223
Ordered Locus Names:Bamb_5014
OrganismBurkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) [Complete proteome] [HAMAP] EMBL ABI90563.1
Taxonomic identifier339670 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length209 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding911Zinc By similarity HAMAP MF_00223
Metal binding941Zinc By similarity HAMAP MF_00223
Metal binding1621Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
Q0B5L0 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 01FD02544B64B6D3

FASTA20923,441
        10         20         30         40         50         60 
MGKKTARPEP VASRPSRKEA EEAVRVLLRW AGDDPAREGL LDTPARVVRA YEEFFAGYAL 

        70         80         90        100        110        120 
EPREILARTF SEVDGYDEMI VLKDIRFESY CEHHMVPIIG RAHVAYLPNH RVVGISKLAR 

       130        140        150        160        170        180 
LVDAFAKRLQ IQEKMTVQIA DTLFDVLQPK GVGVILEAAH QCISTRGIHK PGVEMVTSRM 

       190        200 
LGTFRTDPST RREFLSIVAN PSSVNLTNT

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References

[1]"Complete sequence of chromosome 2 of Burkholderia cepacia AMMD."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K., Ramette A., Tiedje J., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000441 Genomic DNA. Translation: ABI90563.1.
RefSeqYP_776897.1. NC_008391.1.

3D structure databases

ProteinModelPortalQ0B5L0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0B5L0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4313905.
GenomeReviewsGene locus Bamb_5014 in contig CP000441_GR.
KEGGbam:Bamb_5014.
NMPDRfig|339670.3.peg.1678.
PATRIC19026015. VBIBurAmb61564_5258.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHBG370191.
OMAGAFRESS.
PhylomeDBQ0B5L0.
ProtClustDBPRK09347.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0B5L0_BURCM
AccessionPrimary (citable) accession number: Q0B5L0
Entry history
Integrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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