ID   XYLA_BURCM              Reviewed;         440 AA.
AC   Q0B1U7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Xylose isomerase;
DE            EC=5.3.1.5;
GN   Name=xylA; OrderedLocusNames=Bamb_6332;
OS   Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia
OS   cepacia (strain AMMD)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=339670;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., Parke J., Coenye T.,
RA   Konstantinidis K., Ramette A., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 3 of Burkholderia cepacia AMMD.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-xylose = D-xylulose.
CC   -!- COFACTOR: Binds 2 magnesium ions per subunit (By similarity).
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the xylose isomerase family.
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DR   EMBL; CP000442; ABI91876.1; -; Genomic_DNA.
DR   RefSeq; YP_778210.1; -.
DR   GeneID; 4315236; -.
DR   GenomeReviews; CP000442_GR; Bamb_6332.
DR   KEGG; bam:Bamb_6332; -.
DR   NMPDR; fig|339670.3.peg.569; -.
DR   OMA; Q0B1U7; QFLIEPK.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0009045; F:xylose isomerase activity; IEA:HAMAP.
DR   GO; GO:0042732; P:D-xylose metabolic process; IEA:HAMAP.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP.
DR   HAMAP; MF_00455; -; 1.
DR   InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR   InterPro; IPR012307; Xyl_isomerase-typ_TIM-brl.
DR   InterPro; IPR013452; Xylose_isom_bac.
DR   InterPro; IPR001998; Xylose_isomerase.
DR   InterPro; IPR018115; Xylose_isomerase_AS.
DR   Gene3D; G3DSA:3.20.20.150; Xyl_isomerase-like_TIM-brl; 1.
DR   Pfam; PF01261; AP_endonuc_2; 1.
DR   PRINTS; PR00688; XYLOSISMRASE.
DR   TIGRFAMs; TIGR02630; xylose_isom_A; 1.
DR   PROSITE; PS51415; XYLOSE_ISOMERASE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Cytoplasm; Isomerase;
KW   Magnesium; Metal-binding; Pentose shunt; Xylose metabolism.
FT   CHAIN         1    440       Xylose isomerase.
FT                                /FTId=PRO_1000026435.
FT   ACT_SITE    100    100       By similarity.
FT   ACT_SITE    103    103       By similarity.
FT   METAL       231    231       Magnesium 1 (By similarity).
FT   METAL       267    267       Magnesium 1 (By similarity).
FT   METAL       267    267       Magnesium 2 (By similarity).
FT   METAL       270    270       Magnesium 2 (By similarity).
FT   METAL       295    295       Magnesium 1 (By similarity).
FT   METAL       306    306       Magnesium 2 (By similarity).
FT   METAL       308    308       Magnesium 2 (By similarity).
FT   METAL       338    338       Magnesium 1 (By similarity).
SQ   SEQUENCE   440 AA;  49531 MW;  ACC9EAFF1BDB28F9 CRC64;
     MSYFEHIPAI RYEGPQSDNP LAYHHYDAEK RVLGKTMAEH LRIAVCYWHT FVWPGHDIFG
     QGAFQRPWQQ PGDALERARL KADAAFEFFT KLGTPFYTFH DTDVAPEGDS LREYAANFAR
     MVDYLGERQQ ASGVRLLWGT ANLFSHPRFA AGAATNPNPD VFAWAATQVC HALDATHRLG
     GENYVLWGGR EGYETLLNTD LKRERDQFAR FLSMVVEHKH RIGFKGALLI EPKPQEPTKH
     QYDYDVATVH GFLVQYGLQN EIRVNIEANH ATLAGHSFHH EIANAFALGV FGSVDANRGD
     PQNGWDTDQF PNSVEELTLA FYEILRHGGF TTGGMNFDAK VRRQSVDPED LFYGHVGAID
     VLALALERAA VLVENDRLDA LRRQRYAQWD DAFGQKILSG GYTLQSLADD ALARGVDPRH
     ASGAQERLEN IVNQAIYGLR
//