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Q0AXY2

- Q0AXY2_SYNWW

UniProt

Q0AXY2 - Q0AXY2_SYNWW

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Protein

Thymidine kinase

Gene

Swol_1112

Organism
Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSWOL335541:GHL1-1143-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:Swol_1112Imported
OrganismiSyntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)Imported
Taxonomic identifieri335541 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSyntrophomonadaceaeSyntrophomonas
ProteomesiUP000001968: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi335541.Swol_1112.

Structurei

3D structure databases

ProteinModelPortaliQ0AXY2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1435.
HOGENOMiHOG000076390.
KOiK00857.
OMAiQAICLSC.
OrthoDBiEOG69D3J2.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0AXY2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGKIEIITGP MFAGKTTELM RRLERYTLAG NNVVLFKPHI DSRTETEIAT
60 70 80 90 100
TSVRQQFSIP VLVLHKPIGI EAAVVAIDEA QFFGEWILTY VQSLKDQGKT
110 120 130 140 150
VIISGLDMDA HRRPFGFMGQ LMAIADSVSK LTAVCRCGED AVYTWLKNSL
160 170
PQPKGNLILI GDSERYEPRC RKCYASKT
Length:178
Mass (Da):19,882
Last modified:October 17, 2006 - v1
Checksum:i6FF370D504C4F03E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000448 Genomic DNA. Translation: ABI68422.1.
RefSeqiYP_753793.1. NC_008346.1.

Genome annotation databases

EnsemblBacteriaiABI68422; ABI68422; Swol_1112.
GeneIDi4283649.
KEGGiswo:Swol_1112.
PATRICi23857031. VBISynWol51738_1177.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000448 Genomic DNA. Translation: ABI68422.1 .
RefSeqi YP_753793.1. NC_008346.1.

3D structure databases

ProteinModelPortali Q0AXY2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 335541.Swol_1112.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI68422 ; ABI68422 ; Swol_1112 .
GeneIDi 4283649.
KEGGi swo:Swol_1112.
PATRICi 23857031. VBISynWol51738_1177.

Phylogenomic databases

eggNOGi COG1435.
HOGENOMi HOG000076390.
KOi K00857.
OMAi QAICLSC.
OrthoDBi EOG69D3J2.

Enzyme and pathway databases

BioCyci SWOL335541:GHL1-1143-MONOMER.

Family and domain databases

InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of Syntrophomonas wolfei: new insights into syntrophic metabolism and biohydrogen production."
    Sieber J.R., Sims D.R., Han C., Kim E., Lykidis A., Lapidus A.L., McDonnald E., Rohlin L., Culley D.E., Gunsalus R., McInerney M.J.
    Environ. Microbiol. 12:2289-2301(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 2245B / GoettingenImported.

Entry informationi

Entry nameiQ0AXY2_SYNWW
AccessioniPrimary (citable) accession number: Q0AXY2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: November 26, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3