ID   Q0AV12_SYNWW            Unreviewed;       656 AA.
AC   Q0AV12;
DT   17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   17-OCT-2006, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   SubName: Full=Putative methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ABI69442.1};
GN   OrderedLocusNames=Swol_2151 {ECO:0000313|EMBL:ABI69442.1};
OS   Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Syntrophomonadaceae;
OC   Syntrophomonas.
OX   NCBI_TaxID=335541 {ECO:0000313|EMBL:ABI69442.1, ECO:0000313|Proteomes:UP000001968};
RN   [1] {ECO:0000313|Proteomes:UP000001968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2245B / Goettingen {ECO:0000313|Proteomes:UP000001968};
RX   PubMed=21966920; DOI=10.1111/j.1462-2920.2010.02237.x;
RA   Sieber J.R., Sims D.R., Han C., Kim E., Lykidis A., Lapidus A.L.,
RA   McDonnald E., Rohlin L., Culley D.E., Gunsalus R., McInerney M.J.;
RT   "The genome of Syntrophomonas wolfei: new insights into syntrophic
RT   metabolism and biohydrogen production.";
RL   Environ. Microbiol. 12:2289-2301(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000448; ABI69442.1; -; Genomic_DNA.
DR   RefSeq; WP_011641533.1; NC_008346.1.
DR   AlphaFoldDB; Q0AV12; -.
DR   STRING; 335541.Swol_2151; -.
DR   KEGG; swo:Swol_2151; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   OrthoDB; 243053at2; -.
DR   Proteomes; UP000001968; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001968};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        278..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          298..350
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          369..605
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   656 AA;  71115 MW;  3AD25A2BAE795282 CRC64;
     MKFTQSLKFN FLLWILGAFF LASIGQSLVS YWSGKDILIQ QIQENCTQIA DATGDEIDAW
     IAGKFSEMST LAKLDEVRNL DAERLPALLS GLMSADHDNL YVVWPDGTVV GDTGLQDFKL
     DERNYFKLAM AGKANIDTPV ISKATGNLVA PIAVPIYQGD KVVGVLGATI KAEKITEITS
     DVKVGETGYA YLINQDTTFV AHPKKDYILQ KKLSDDAEGM EDVIKRMTAL ETGIAEYEYD
     GEVKYMAYDP VHLAGWSLAV TVPVSEVTQP LDAMLHKMIM VTIVTLLLLS IIIWFVTGRL
     TKPILGMVDI TTRLSQRDLT QEIESRNRSE IGLLMNSLRD MNENLNTVLK QMAGSSERLA
     SVSEDLMQTA RQTGQASEQV SASAEEVARA ATAEAEDAQK TSELVQQVGM AMQNVGSTTE
     AISSQSLNFK SIVGRVTGLM LRQKDEMALT VNSTVNVAGV IEELSNKTQE IGEIINVINN
     IAGQTNLLAL NAAIEAARAG EAGRGFAVVA EEVRKLAEET GSATLNIATI INEVQAGVER
     AVTEVDKVEK QVREQGVSLG ESVDSFREIE QGAVEIDNAI QDISATFEEL LASADEMTQA
     IENISAATEE SAASAEEVTA ISQNQLAAVQ NIVAVSQELD KLAVELKKVT DTFKLK
//