ID   Q0AV01_SYNWW            Unreviewed;       665 AA.
AC   Q0AV01;
DT   17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   17-OCT-2006, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Putative methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ABI69453.1};
GN   OrderedLocusNames=Swol_2162 {ECO:0000313|EMBL:ABI69453.1};
OS   Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Syntrophomonadaceae;
OC   Syntrophomonas.
OX   NCBI_TaxID=335541 {ECO:0000313|EMBL:ABI69453.1, ECO:0000313|Proteomes:UP000001968};
RN   [1] {ECO:0000313|Proteomes:UP000001968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2245B / Goettingen {ECO:0000313|Proteomes:UP000001968};
RX   PubMed=21966920; DOI=10.1111/j.1462-2920.2010.02237.x;
RA   Sieber J.R., Sims D.R., Han C., Kim E., Lykidis A., Lapidus A.L.,
RA   McDonnald E., Rohlin L., Culley D.E., Gunsalus R., McInerney M.J.;
RT   "The genome of Syntrophomonas wolfei: new insights into syntrophic
RT   metabolism and biohydrogen production.";
RL   Environ. Microbiol. 12:2289-2301(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000448; ABI69453.1; -; Genomic_DNA.
DR   RefSeq; WP_011641544.1; NC_008346.1.
DR   AlphaFoldDB; Q0AV01; -.
DR   STRING; 335541.Swol_2162; -.
DR   KEGG; swo:Swol_2162; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   OrthoDB; 9814363at2; -.
DR   Proteomes; UP000001968; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd12914; PDC1_DGC_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001968};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          304..359
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          364..650
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   665 AA;  70858 MW;  6DD66F3EF40FE83D CRC64;
     MKSIGSRLTL YISMVVLFFC AGLGFISYFY ASKALMANIE QSVVAKAQDA TKLVGSELDN
     HLSVMETIAE QPEITSMKWE EQRPILEQAN KRLGYLMMGV AGLDGQVLTT AGSTTNLKDR
     DYFDQALKGQ SSVSDPIVSR IDGNTIVMMV SPIRGTEGEV IGVLAAALDG LILSQIIAGV
     NFSDSGYAYM LNRQGQVIAH PKEEMVIEQY DPIAEADKDP KLAPLAAIVK NMLKAECGYG
     EYLWTDGTNK FMGYAPVENT GWSIAVTAPQ DEVLAGLKSM TVGVLVAALV FLLIGIALAT
     YLGRTLAQPI KNVAGNASLI ADGDLRVEIA AGALARQDEI GHLASSLDNM VQGLRNMLHE
     VALNSQEVAA SSQELAASGE NIASIVEELS ASTEEIAAGI TNISSATDEV NASGEGISSA
     LLLASKDAEQ GVLQAQSIEK RAARMQNGAQ DHKKTAENVY GTIKEKLTAA IEEARVVEQI
     SELAENISGI ASQTNLLALN AAIEAARAGE QGKGFAVVAE EVRKLAENSA SAVEGIQGMT
     EQVQRSIANL TNYAEELLNF INTQIIADYG DMVTICKHYK NDSDMFLNLI EKIKKHTEEV
     LASVEDINHS LDSTAGTIRD SSAGAQKIAE ASQTAAIAAT EISAASVRMA ENAEKLNLLI
     TRFKL
//