Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Arginine--tRNA ligase

Gene

argS

Organism
Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSWOL335541:G1G78-2524-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Swol_2421
OrganismiSyntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
Taxonomic identifieri335541 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSyntrophomonadaceaeSyntrophomonas
Proteomesi
  • UP000001968 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000181391 – 559Arginine--tRNA ligaseAdd BLAST559

Proteomic databases

PRIDEiQ0AU94

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi335541.Swol_2421

Structurei

3D structure databases

ProteinModelPortaliQ0AU94
SMRiQ0AU94
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi134 – 144"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiHGMSTRQ
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q0AU94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPIQKVLAS LHSMVIEALE KAKSRDLIKF DQIPEFLIEV PREKEHGDFA
60 70 80 90 100
CNVALLMARQ ARQAPRAIAE VLVELMEASG RPVEKIEIAG AGFINFFLDR
110 120 130 140 150
SWLYEIPLMV YKSKDKYGFN GEKAKKVQVE FVSANPTGNL HMGNARGGAI
160 170 180 190 200
GDTLANILER AGYEVEREFY INDAGNQIEI FTDSMEARYL QLTGHDVQFP
210 220 230 240 250
ENGYAGRDLI DTVRNIIARY GEGLYDLPRE ERRQIIVDFA LEEKIDYIQK
260 270 280 290 300
TLASFGINYD VWFSEKSLHE NGKIMAVFND LRDKGYIYES EGAWWFKSTA
310 320 330 340 350
FGDEKDEVVL RANGMPTYFM ADIAYHQNKF ERGFDWVINV WGADHHGHVA
360 370 380 390 400
RMKGAIEALG YDPARLDILL MQLVRLYRGG NIVRMSKRTG TTVSLDELIE
410 420 430 440 450
DVGKDAARFF FVMRSPDSHL DFDLELARQK SQENPVYYVQ YAHARICSIF
460 470 480 490 500
RQARAEGITM AEINEIDISC LKEEEELAIL RKIADFPEEI SIAARTLAPH
510 520 530 540 550
RIARYVLDLA ALFHSFYNHH RVLNDNRALQ DARLLLMEIT RITIHNALDV

LGVAAPEQM
Length:559
Mass (Da):63,845
Last modified:October 17, 2006 - v1
Checksum:iBDB8DA6E5A61D822
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000448 Genomic DNA Translation: ABI69710.1
RefSeqiWP_011641794.1, NC_008346.1

Genome annotation databases

EnsemblBacteriaiABI69710; ABI69710; Swol_2421
KEGGiswo:Swol_2421

Similar proteinsi

Entry informationi

Entry nameiSYR_SYNWW
AccessioniPrimary (citable) accession number: Q0AU94
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 17, 2006
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health