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Q0ATH6 (UPPP_MARMM) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Mmar10_0115
OrganismMaricaulis maris (strain MCS10) [Complete proteome] [HAMAP]
Taxonomic identifier394221 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeMaricaulis

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 268268Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000290724

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane110 – 13021Helical; Potential
Transmembrane144 – 16421Helical; Potential
Transmembrane187 – 20721Helical; Potential
Transmembrane221 – 24121Helical; Potential
Transmembrane247 – 26721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q0ATH6 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: C9E8473B04ED76AD

FASTA26828,004
        10         20         30         40         50         60 
MSLIYLVVLA LVQGITEFLP ISSSAHLILA PQVLGQADQG PLIDVMAHAG SLLAVLVYFR 

        70         80         90        100        110        120 
SDIVSVAMGK LALLQGRVTP GGRLALLVAA SMPPIIIVAG ALVAFDLVDA LRSPRVIAIA 

       130        140        150        160        170        180 
TLAFALPLWL ADRYGRQTIT IETMSFKHAA LIGIAQLFAL IPGASRSGVT MTAARGLGLT 

       190        200        210        220        230        240 
RTDSARFSML MAIPVIAAFG LVSLIELVRA DGMAAGASLS DGLIVAGLSF VTAWAAIAVL 

       250        260 
MRLVERIGFL PFALYRVGLG LALLVFFV 

« Hide

References

[1]"Complete sequence of Maricaulis maris MCS10."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Viollier P., Stephens C., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MCS10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000449 Genomic DNA. Translation: ABI64411.1.
RefSeqYP_755349.1. NC_008347.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING394221.Mmar10_0115.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI64411; ABI64411; Mmar10_0115.
GeneID4283823.
KEGGmmr:Mmar10_0115.
PATRIC22448218. VBIMarMar77530_0120.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMALVGCFQC.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycMMAR394221:GHNB-120-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_MARMM
AccessionPrimary (citable) accession number: Q0ATH6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: October 17, 2006
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families