UniProtKB - Q0ASJ7 (TRUA_MARMM)
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Protein
tRNA pseudouridine synthase A
Gene
truA
Organism
Maricaulis maris (strain MCS10)
Status
Functioni
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation
Catalytic activityi
tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 52 | NucleophileUniRule annotation | 1 | |
Binding sitei | 111 | SubstrateUniRule annotation | 1 |
GO - Molecular functioni
- pseudouridine synthase activity Source: UniProtKB-EC
- RNA binding Source: InterPro
GO - Biological processi
- pseudouridine synthesis Source: InterPro
- tRNA processing Source: UniProtKB-KW
Keywordsi
Molecular function | Isomerase |
Biological process | tRNA processing |
Enzyme and pathway databases
BioCyci | MMAR394221:G1G79-464-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)Alternative name(s): tRNA pseudouridine(38-40) synthaseUniRule annotation tRNA pseudouridylate synthase IUniRule annotation tRNA-uridine isomerase IUniRule annotation |
Gene namesi | Name:truAUniRule annotation Ordered Locus Names:Mmar10_0447 |
Organismi | Maricaulis maris (strain MCS10) |
Taxonomic identifieri | 394221 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Hyphomonadaceae › Maricaulis › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000017109 | 1 – 249 | tRNA pseudouridine synthase AAdd BLAST | 249 |
Interactioni
Subunit structurei
Homodimer.UniRule annotation
Protein-protein interaction databases
STRINGi | 394221.Mmar10_0447 |
Structurei
3D structure databases
ProteinModelPortali | Q0ASJ7 |
SMRi | Q0ASJ7 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG4105DI7 Bacteria COG0101 LUCA |
HOGENOMi | HOG000248672 |
KOi | K06173 |
OMAi | FLYGMVR |
OrthoDBi | POG091H010Q |
Family and domain databases
Gene3Di | 3.30.70.6601 hit |
HAMAPi | MF_00171 TruA, 1 hit |
InterProi | View protein in InterPro IPR020103 PsdUridine_synth_cat_dom_sf IPR001406 PsdUridine_synth_TruA IPR020097 PsdUridine_synth_TruA_a/b_dom IPR020095 PsdUridine_synth_TruA_C |
PANTHERi | PTHR11142 PTHR11142, 1 hit |
Pfami | View protein in Pfam PF01416 PseudoU_synth_1, 2 hits |
PIRSFi | PIRSF001430 tRNA_psdUrid_synth, 1 hit |
SUPFAMi | SSF55120 SSF55120, 1 hit |
TIGRFAMsi | TIGR00071 hisT_truA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q0ASJ7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPRYRITIEY DGRPFSGWQR QDNAPSVQES LERAAEKLDG APVLVYGAGR
60 70 80 90 100
TDSGVHALAQ VAHLDLAKDL STDKVRDAIN YHLKPDPVAV IEAARVSDDF
110 120 130 140 150
HARFSATRRH YLYRMIDRRA PLTLDRGQVW RVTRKLDAEA MHHAAQALLG
160 170 180 190 200
QHDFTTFRDA QCQAESPVKS LDAISVSRYG EEVQLTCSAR SFLHRQVRSM
210 220 230 240
VGSLVEVGVG KWSARDFKRA LDAADRSRCG PVAPADGLYL TAVDYPGPA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000449 Genomic DNA Translation: ABI64740.1 |
RefSeqi | WP_011642387.1, NC_008347.1 |
Genome annotation databases
EnsemblBacteriai | ABI64740; ABI64740; Mmar10_0447 |
KEGGi | mmr:Mmar10_0447 |
Similar proteinsi
Entry informationi
Entry namei | TRUA_MARMM | |
Accessioni | Q0ASJ7Primary (citable) accession number: Q0ASJ7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 15, 2008 |
Last sequence update: | October 17, 2006 | |
Last modified: | February 28, 2018 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |