Reviewed, UniProtKB/Swiss-Prot Q0AQP4 (PCKA_MARMM)

Names and origin

Protein names

Recommended name:
    Phosphoenolpyruvate carboxykinase [ATP]
      Short name=PEP carboxykinase
      Short name=PEPCK
    EC=4.1.1.49
Alternative name(s):
    Phosphoenolpyruvate carboxylase

Gene names

Name:	pckA
Ordered Locus Names:	Mmar10_1100

Organism

Maricaulis maris (strain MCS10) [Complete proteome] [HAMAP]

Taxonomic identifier

394221 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Hyphomonadaceae › Maricaulis

Protein attributes

Sequence length	537 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2. HAMAP MF_00453
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00453
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the phosphoenolpyruvate carboxykinase [ATP] family.

Ontologies

Keywords
Biological process	Gluconeogenesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxykinase (ATP) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 537	537	Phosphoenolpyruvate carboxykinase [ATP] HAMAP MF_00453		PRO_1000026331
Regions
	Nucleotide binding	234 – 241	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0AQP4-1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 22AEF8CF40682D25	FASTA	537	58,282
	10 20 30 40 50 60 MSKSERLDGG LEALGIQAGT VNLNWNEPRL YQEAVQRGEA EVAEGGALVV KTGAHTGRSA 70 80 90 100 110 120 KDKFTVRDSE TEDQVWWDNN AAISPEHFDA LWTDFQAHMA GKELFVQQLF GGADLDHRLP 130 140 150 160 170 180 VRVVNELAWH SLFIRHLLRV PAAEEYAGFA AEFTIINLPS FKADPARHGC RSETVIGVDF 190 200 210 220 230 240 ARRIVLIGGT SYAGETKKSV FTILNYLLPA KGVMPMHCSV NSNPNGEDAT IFFGLSGTGK 250 260 270 280 290 300 TTLSADASRT LVGDDEHGWS PNGLFNFEGG CYAKMIRLSA EAEPEIHATT KMWGTVLENV 310 320 330 340 350 360 VMDPQTRVLD LDDDSLAENS RGAYPLSAIP NASETGRCGH PKNVIMLTCD AFGIMPPIAK 370 380 390 400 410 420 LTPAQAMYHF LSGYTAKVAG TEKGVTEPSA TFSTCFGAPF MPRHPAEYGA LLRELIAEHQ 430 440 450 460 470 480 VDCWLVNTGW TGGAYGTGNR MPIKATRALL NAAMDGSLNS AAFREDPNFG FMVPIAVDGV 490 500 510 520 530 DASILDPRST WSDKAAYDDR AAKLATMFIE NFKTFEAHVA PYVRAAAPKV RELTAAE

References

[1]

"Complete sequence of Maricaulis maris MCS10." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Viollier P., Stephens C., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000449 Genomic DNA. Translation: ABI65393.1.
RefSeq	YP_756331.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4284274.
GenomeReviews	Gene locus Mmar10_1100 in contig CP000449_GR.
KEGG	mmr:Mmar10_1100.
NMPDR	fig|394221.5.peg.1071.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0AQP4.
OMA	Q0AQP4. ELAWHSL.
Family and domain databases
HAMAP	MF_00453. [Tree]
InterPro	IPR001272. PEP_carboxykinase_ATP. IPR013035. PEP_carboxykinase_C. IPR008210. PEP_carboxykinase_N. IPR015994. PEPCK_ATP_CS. [Graphical view]
Gene3D	G3DSA:3.90.228.20. PEP_carboxykinase_C. 1 hit. G3DSA:3.40.449.10. PEP_carboxykinase_N. 1 hit.
Pfam	PF01293. PEPCK_ATP. 1 hit. [Graphical view]
PIRSF	PIRSF006294. PEP_crbxkin. 1 hit.
ProDom	PD004738. PEPCK_N. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00224. pckA. 1 hit.
PROSITE	PS00532. PEPCK_ATP. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PCKA_MARMM

Accession

Primary (citable) accession number: Q0AQP4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 17, 2006
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)