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Protein

Guanylate kinase

Gene

gmk

Organism
Maricaulis maris (strain MCS10)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 31ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR394221:G1G79-1274-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:Mmar10_1220
OrganismiMaricaulis maris (strain MCS10)
Taxonomic identifieri394221 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeMaricaulis
Proteomesi
  • UP000001964 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002663451 – 218Guanylate kinaseAdd BLAST218

Interactioni

Protein-protein interaction databases

STRINGi394221.Mmar10_1220

Structurei

3D structure databases

ProteinModelPortaliQ0AQC4
SMRiQ0AQC4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 196Guanylate kinase-likeUniRule annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037638
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q0AQC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDGYPAPI FRGRRRGVLL ALSSPSGAGK TTLSKRLLSQ NPDVVLSVSA
60 70 80 90 100
TTRKPRPGEV DGQDYHFISV DEFKKKIEDD EFFEWAEVFG RYYGTPKTPV
110 120 130 140 150
MEAVEDGRDV VFDIDWQGAQ ALAAAAPDDA VRVFILPPSL ALLEDRLRKR
160 170 180 190 200
GQDTTEIIKD RMARAKDEIS HWHEYDYVIV NDDFARALEK LNEILHAERL
210
KRLRHPWLEE FVDAIMEQ
Length:218
Mass (Da):24,888
Last modified:October 17, 2006 - v1
Checksum:i98C4A3C62124C229
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000449 Genomic DNA Translation: ABI65513.1
RefSeqiWP_011643160.1, NC_008347.1

Genome annotation databases

EnsemblBacteriaiABI65513; ABI65513; Mmar10_1220
KEGGimmr:Mmar10_1220

Similar proteinsi

Entry informationi

Entry nameiKGUA_MARMM
AccessioniPrimary (citable) accession number: Q0AQC4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 17, 2006
Last modified: March 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health