Q0APM5 (KYNB_MARMM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Kynurenine formamidase
Short name=KFA
EC=3.5.1.9

Alternative name(s):
N-formylkynurenine formamidase

Gene names

Name:	kynB
Ordered Locus Names:	Mmar10_1470

Organism

Maricaulis maris (strain MCS10) [Complete proteome] [HAMAP]

Taxonomic identifier

394221 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Hyphomonadaceae › Maricaulis

Protein attributes

Sequence length	209 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine By similarity.
Catalytic activity	N-formyl-L-kynurenine + H2O = formate + L-kynurenine.
Pathway	Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.
Sequence similarities	Belongs to the kynB family.

Ontologies

Keywords
Biological process	Tryptophan catabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	anthranilate metabolic process Inferred from sequence or structural similarity. Source: UniProtKB tryptophan catabolic process to kynurenine Inferred from sequence or structural similarity. Source: UniProtKB
Molecular function	arylformamidase activity Inferred from sequence or structural similarity. Source: UniProtKB formamidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 209	209	Kynurenine formamidase		PRO_0000362125

Sequences

	Sequence		Length	Mass (Da)
	Q0APM5 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: A6FC281C63DC8BCA	FASTA	209	22,546
	10 20 30 40 50 60 MAKMWDISQT LRPDLPVWPG DTAFACDEVW SIGPDCPVQV SRLTLSTHSG AHADAPSHYD 70 80 90 100 110 120 QAGDDIASTP LELYVGPCRL VTASGNGPHV QPADLDWAAI DGATRVLVRT YAKFPADDWD 130 140 150 160 170 180 PDFRALHADT IERLAATGCR LIGVDAASLD PQTSKTMDAH HAVQRHDMRI LEGLVFDGVP 190 200 DGHYELIALP LKIAGADAAP LRAVLRELP

References

[1]

"Complete sequence of Maricaulis maris MCS10." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Viollier P., Stephens C., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MCS10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000449 Genomic DNA. Translation: ABI65762.1.
RefSeq	YP_756700.1. NC_008347.1.
3D structure databases
ProteinModelPortal	Q0APM5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0APM5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4284580.
GenomeReviews	Gene locus Mmar10_1470 in contig CP000449_GR.
KEGG	mmr:Mmar10_1470.
NMPDR	fig|394221.5.peg.1435.
PATRIC	22451036. VBIMarMar77530_1507.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1878.
HOGENOM	HBG686791.
OMA	HTSKWPL.
Enzyme and pathway databases
BioCyc	MMAR394221:MMAR10_1470-MONOMER.
Family and domain databases
InterPro	IPR017484. Arylformamidase. IPR007325. Cyclase. [Graphical view]
KO	K07130.
Pfam	PF04199. Cyclase. 1 hit. [Graphical view]
TIGRFAMs	TIGR03035. Trp_arylform. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KYNB_MARMM

Accession

Primary (citable) accession number: Q0APM5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	October 17, 2006
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program