Q0ANE1 (SURE_MARMM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	Mmar10_1904

Organism

Maricaulis maris (strain MCS10) [Complete proteome] [HAMAP]

Taxonomic identifier

394221 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Hyphomonadaceae › Maricaulis

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 264	264	5'-nucleotidase surE HAMAP MF_00060		PRO_0000335262
Sites
	Metal binding	13	1	Divalent metal cation By similarity
	Metal binding	14	1	Divalent metal cation By similarity
	Metal binding	45	1	Divalent metal cation By similarity
	Metal binding	98	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0ANE1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 90F25B9B2CD30BBE	FASTA	264	29,274
	10 20 30 40 50 60 MIPENPRILL TNDDGIRAHG LKVLEKIARQ LSDDVWIVAP AEEQSGAGRS LSLHDPLRVR 70 80 90 100 110 120 RFDERRMSVS GTPTDCVLMG IQDLIPGKQP DLVLSGVNRG QNIAEDVTFS GTVAGAMQGM 130 140 150 160 170 180 QLGIPSVALS QAYGFGKDDP IQWETAEMYG APILRRLFDL KWPDDVLINI NFPDRKPGDV 190 200 210 220 230 240 EEVEVTRQGR RDQHILHAEH RVDPRGMDYY WLAFKGLLSN PPDGVDLRAI YDGKISVTPL 250 260 HMDLTHGETL GNLKRMLGGV PPKS

References

[1]

"Complete sequence of Maricaulis maris MCS10." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Viollier P., Stephens C., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MCS10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000449 Genomic DNA. Translation: ABI66196.1.
RefSeq	YP_757134.1. NC_008347.1.
3D structure databases
ProteinModelPortal	Q0ANE1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0ANE1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4286422.
GenomeReviews	Gene locus Mmar10_1904 in contig CP000449_GR.
KEGG	mmr:Mmar10_1904.
NMPDR	fig|394221.5.peg.1866.
PATRIC	22451960. VBIMarMar77530_1952.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	PGHIVAA.
PhylomeDB	Q0ANE1.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	MMAR394221:MMAR10_1904-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_MARMM

Accession

Primary (citable) accession number: Q0ANE1

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	October 17, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program