Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Thymidine kinase

Gene

tdk

Organism
Maricaulis maris (strain MCS10)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei91Proton acceptorUniRule annotation1
Metal bindingi148ZincUniRule annotation1
Metal bindingi150ZincUniRule annotation1
Metal bindingi184ZincUniRule annotation1
Metal bindingi187ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi9 – 16ATPUniRule annotation8
Nucleotide bindingi90 – 93ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Mmar10_2037Imported
OrganismiMaricaulis maris (strain MCS10)Imported
Taxonomic identifieri394221 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeMaricaulis
Proteomesi
  • UP000001964 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi394221.Mmar10_2037.

Structurei

3D structure databases

ProteinModelPortaliQ0AN08.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107104. Bacteria.
COG1435. LUCA.
HOGENOMiHOG000076391.
KOiK00857.
OMAiKEQFGWI.
OrthoDBiPOG091H0659.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase. 1 hit.
InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0AN08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKLYFTYSA MNAGKSAILL QAAHNYGERG MSAMLWTSVH HAADPGARTG
60 70 80 90 100
QIESRIGLKA PARIFAPETD LFAAIKAQAG AAALDAVFFD EAQFLTASQV
110 120 130 140 150
RDLARVVDVL GLPVLCYGLR TDFRGALFPG SAELLALADH LREVRTVCHC
160 170 180 190
GRKATMNLRR QPDGRAVAEG EQVAVEKADY VSLCRKHFFE ALAG
Length:194
Mass (Da):20,983
Last modified:October 17, 2006 - v1
Checksum:i99768E532238B036
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000449 Genomic DNA. Translation: ABI66329.1.
RefSeqiWP_011643974.1. NC_008347.1.

Genome annotation databases

EnsemblBacteriaiABI66329; ABI66329; Mmar10_2037.
KEGGimmr:Mmar10_2037.

Similar proteinsi

Entry informationi

Entry nameiQ0AN08_MARMM
AccessioniPrimary (citable) accession number: Q0AN08
Entry historyiIntegrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: September 27, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported