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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Maricaulis maris (strain MCS10)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR394221:G1G79-2300-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Mmar10_2213
OrganismiMaricaulis maris (strain MCS10)
Taxonomic identifieri394221 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeMaricaulis
Proteomesi
  • UP000001964 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180561 – 588Arginine--tRNA ligaseAdd BLAST588

Proteomic databases

PRIDEiQ0AMI8

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi394221.Mmar10_2213

Structurei

3D structure databases

ProteinModelPortaliQ0AMI8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi124 – 134"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q0AMI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSIADQLSA VLGDAFASLE LPRELGRVSP SKQKPEVFPF QCNGAMPAAK
60 70 80 90 100
QAKTNPRELA AKLIEALHGI PQIGAAEIAG PGFINLRPAE HLYGERAAEI
110 120 130 140 150
AGDDRAGAPL AAAPRTVMID FGGPNVAKPM HVGHLRSSVL GDSLQRLFRF
160 170 180 190 200
RGDTVVSDIH LGDWGLQMGH LITELHEEQP DLVYFDAAIT DGYPSEPPVT
210 220 230 240 250
IEDLARLYPQ ASVKAKAGPE RLEISRSATA ELQAGRPGYR ALLRHFIDVS
260 270 280 290 300
VAALKRDFGA LGVHFDLWKG ESDVDPLIPG LVEDFKARGV AEESEGALIV
310 320 330 340 350
RVARDGDKKE LAPLILVSKT GAALYGTTDL ATILDRKQSV DPDLTLYVVD
360 370 380 390 400
LAQGDHFEQV FRAAEKAGLA EEGALEHVKF GTVNGTDGKR LRTRDGGTFR
410 420 430 440 450
LADLIASAIE RADERLKEAG LAADVSAEEH ARVARMVGLA AIKFADLQNY
460 470 480 490 500
RTTNYVFDLD RFTSFEGKTG PYLLYAAVRV KSLMRRAAEA GVTPGEILVD
510 520 530 540 550
AQEERDLVLC LDAFGAALDN AADNRAPNAL CDHAFTLAQA FSKFYSACPV
560 570 580
LVAEDDAVKA SRLALAEATL KQLELCLGLL GLEAPERM
Length:588
Mass (Da):63,300
Last modified:October 17, 2006 - v1
Checksum:iED9AF4387C634B50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000449 Genomic DNA Translation: ABI66505.1
RefSeqiWP_011644150.1, NC_008347.1

Genome annotation databases

EnsemblBacteriaiABI66505; ABI66505; Mmar10_2213
KEGGimmr:Mmar10_2213

Similar proteinsi

Entry informationi

Entry nameiSYR_MARMM
AccessioniPrimary (citable) accession number: Q0AMI8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 17, 2006
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families
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