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Q0AK73

- TRMB_MARMM

UniProt

Q0AK73 - TRMB_MARMM

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, Mmar10_3039
Organism
Maricaulis maris (strain MCS10)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei60 – 601S-adenosyl-L-methionine By similarity
Binding sitei85 – 851S-adenosyl-L-methionine By similarity
Binding sitei112 – 1121S-adenosyl-L-methionine By similarity
Active sitei134 – 1341 By similarity
Binding sitei134 – 1341S-adenosyl-L-methionine By similarity
Binding sitei138 – 1381Substrate By similarity
Binding sitei170 – 1701Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMMAR394221:GHNB-3093-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:Mmar10_3039
OrganismiMaricaulis maris (strain MCS10)
Taxonomic identifieri394221 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeMaricaulis
ProteomesiUP000001964: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 228228tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
PRO_0000288175Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi394221.Mmar10_3039.

Structurei

3D structure databases

ProteinModelPortaliQ0AK73.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni208 – 2114Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000073969.
KOiK03439.
OMAiRAFYGRR.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0AK73-1 [UniParc]FASTAAdd to Basket

« Hide

MTTEPTQNPA FRLFGRSQGK PLSARQQRLV DEFLPRIGLP DDGPIDPAAL    50
MPDRRRQALE IGFGGGEHLV AQAEANPQTG FIGIEPFLNG VAKALTAIDA 100
AGLGNVRLAR ADAREILPRF ETASLDQIFL LFPDPWHKKR HAKRRFVQQS 150
TRDEFARLLK PGGRLRIATD VKSYADHCMV ELSGDDRFIW QARTADDWTL 200
PPADHITTRY ETKNLGDCAP VFMDFLRV 228
Length:228
Mass (Da):25,559
Last modified:October 17, 2006 - v1
Checksum:i6EBD74E465DE48EE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000449 Genomic DNA. Translation: ABI67320.1.
RefSeqiWP_011644964.1. NC_008347.1.
YP_758258.1. NC_008347.1.

Genome annotation databases

EnsemblBacteriaiABI67320; ABI67320; Mmar10_3039.
GeneIDi4284258.
KEGGimmr:Mmar10_3039.
PATRICi22454312. VBIMarMar77530_3121.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000449 Genomic DNA. Translation: ABI67320.1 .
RefSeqi WP_011644964.1. NC_008347.1.
YP_758258.1. NC_008347.1.

3D structure databases

ProteinModelPortali Q0AK73.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 394221.Mmar10_3039.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI67320 ; ABI67320 ; Mmar10_3039 .
GeneIDi 4284258.
KEGGi mmr:Mmar10_3039.
PATRICi 22454312. VBIMarMar77530_3121.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000073969.
KOi K03439.
OMAi RAFYGRR.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci MMAR394221:GHNB-3093-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MCS10.

Entry informationi

Entry nameiTRMB_MARMM
AccessioniPrimary (citable) accession number: Q0AK73
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: October 17, 2006
Last modified: September 3, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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