Q0AHC3 (GLMM_NITEC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Neut_1000

Organism

Nitrosomonas eutropha (strain C91) [Complete proteome] [HAMAP]

Taxonomic identifier

335283 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Nitrosomonadaceae › Nitrosomonas

Protein attributes

Sequence length	458 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 458	458	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000301348
Sites
	Active site	108	1	Phosphoserine intermediate By similarity
	Metal binding	108	1	Magnesium; via phosphate group By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
	Metal binding	251	1	Magnesium By similarity
Amino acid modifications
	Modified residue	108	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0AHC3 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 662A892F04DA02B9	FASTA	458	50,040
	10 20 30 40 50 60 MKKKYFGTDG IRGKVGEFPI TPEFFLRLGY AVGKVLLASD WKLAADKRPT ILIGKDTRIS 70 80 90 100 110 120 GYMLESALEA GFSAAGVDVL LSGPLPTPAV AYLVRALRIQ AGAVISASHN PFYDNGIKFF 130 140 150 160 170 180 SSEGSKLPDS MELQIEAELD FPIETAPSIK LGRVQRLKDE EGRYIEFCKS TFPNQLDLRG 190 200 210 220 230 240 WKIVVDCANG ADYQVAGHVM HELGADVVTI HANPDGFNIN HECGATHIMT LQGAVLQHGA 250 260 270 280 290 300 DFGIAVDGDG DRVLMVSGEG VVYDGDSLAY IIAKHRQQRG VLQGGVVGTL MTNLAVEQAF 310 320 330 340 350 360 ERIGIPFARA NVGDRYVSEL LQQNDWYLGA ENSGHIICRD KHTTGDGIIS ALQVLYALRD 370 380 390 400 410 420 TGLMFADLMH DVTFFPQRLI NVKISRDFDF QNDQAVEICK NEAEQALGND GRILLRASGT 430 440 450 EPLIRVMVEG KDPQQIEYWA EKIAGTIQQQ AVASTVGH

References

[1]

"Whole-genome analysis of the ammonia-oxidizing bacterium, Nitrosomonas eutropha C91: implications for niche adaptation." Stein L.Y., Arp D.J., Berube P.M., Chain P.S., Hauser L., Jetten M.S., Klotz M.G., Larimer F.W., Norton J.M., Op den Camp H.J.M., Shin M., Wei X. Environ. Microbiol. 9:2993-3007(2007) [PubMed: 17991028] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C91.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000450 Genomic DNA. Translation: ABI59259.1.
RefSeq	YP_747224.1. NC_008344.1.
3D structure databases
ProteinModelPortal	Q0AHC3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0AHC3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4274152.
GenomeReviews	Gene locus Neut_1000 in contig CP000450_GR.
KEGG	net:Neut_1000.
NMPDR	fig|335283.3.peg.2150.
PATRIC	22719199. VBINitEut7577_1266.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	PLEDIQV.
PhylomeDB	Q0AHC3.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	NEUT335283:NEUT_1000-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_NITEC

Accession

Primary (citable) accession number: Q0AHC3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	October 17, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program