Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0AG57

- SYL_NITEC

UniProt

Q0AG57 - SYL_NITEC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Nitrosomonas eutropha (strain C91)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei627 – 6271ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNEUT335283:GHT6-1456-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:Neut_1429
OrganismiNitrosomonas eutropha (strain C91)
Taxonomic identifieri335283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosomonas
ProteomesiUP000001966: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 868868Leucine--tRNA ligasePRO_1000009378Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi335283.Neut_1429.

Structurei

3D structure databases

ProteinModelPortaliQ0AG57.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi42 – 5211"HIGH" regionAdd
BLAST
Motifi624 – 6285"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200747.
KOiK01869.
OMAiPVIHCPK.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 2 hits.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0AG57-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQEKYHPQEI EQQARQSWQE TGIFNTTEIP DKPKYYCLSM FPYPSGKLHM
60 70 80 90 100
GHVRNYTIGD VLSRYRRMQG YNVMQPMGWD AFGLPAENAA IQKGVPPAKW
110 120 130 140 150
TYDNIAYMRS QLQSLGLAID WKRELATCDP EYYRWNQWLF LRMLEKGIAY
160 170 180 190 200
QKTQVVNWDP VDQTVLANEQ VIDGCGWRTG AVVEKREIPG YYLAITRYAD
210 220 230 240 250
ELLAGLENLP GWPERVKAMQ ANWIGKSYGV DIIFSPDIAS GMPQALKVFT
260 270 280 290 300
TRADTLMGAT YVAVAAEHPV ALYAAQNQPK LAAFIESCRQ GATMEAELAL
310 320 330 340 350
QEKKGMATGL YVLHPLTGER LPVWVANYVL MSYGEGAVMA VPAHDERDFD
360 370 380 390 400
FARQYALPIR PVIKPEDGEL PAPLAQAFTG YGVTFDSGEF SSLKSMDAVD
410 420 430 440 450
AIATKLKLEE QGEKRVRYRL RDWGISRQRY WGCPIPLVHC DQCGVVPVPD
460 470 480 490 500
DQLPVTLPED LVPDGSGNPL TKTPSFYECT CPRCGQQAHR ETDTMDTFVD
510 520 530 540 550
SSWYFIRYAC QDQQAAMTDQ RANYWLPVDQ YIGGIEHAIL HLLYSRFWSK
560 570 580 590 600
VMRDLGLVSF DEPFANLLTQ GMVLNEIFFR KTGNGRIQYF NPVEVDVQYD
610 620 630 640 650
AEGKKIGAVL QADGQPVESG GIGTMSKSKN NGIDPQEIIE QYGADTARLF
660 670 680 690 700
MMFASPPTQT LEWSDAGVEG AFRFLKRLWR QVYLHRQQGS DMSATDAIPH
710 720 730 740 750
LEYPADLRDL RCQLHQTIVK VTDDLERRHT FNTAIAAVME LMNKLAGVQD
760 770 780 790 800
ISPAARQLMQ EALENSVLLL SPIVPHICHI LWRELRPGTE LLDQPWPQAD
810 820 830 840 850
EQALIQDEIE IVVQINGKLR GQIRIAREAD QATIERIALE HEHVQRNIAG
860
QPIRKVVIVP GRLVNIVV
Length:868
Mass (Da):98,169
Last modified:October 17, 2006 - v1
Checksum:i91196E00FCE9842F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000450 Genomic DNA. Translation: ABI59675.1.
RefSeqiYP_747640.1. NC_008344.1.

Genome annotation databases

EnsemblBacteriaiABI59675; ABI59675; Neut_1429.
GeneIDi4272733.
KEGGinet:Neut_1429.
PATRICi22720221. VBINitEut7577_1770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000450 Genomic DNA. Translation: ABI59675.1 .
RefSeqi YP_747640.1. NC_008344.1.

3D structure databases

ProteinModelPortali Q0AG57.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 335283.Neut_1429.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI59675 ; ABI59675 ; Neut_1429 .
GeneIDi 4272733.
KEGGi net:Neut_1429.
PATRICi 22720221. VBINitEut7577_1770.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200747.
KOi K01869.
OMAi PVIHCPK.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci NEUT335283:GHT6-1456-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 2 hits.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Whole-genome analysis of the ammonia-oxidizing bacterium, Nitrosomonas eutropha C91: implications for niche adaptation."
    Stein L.Y., Arp D.J., Berube P.M., Chain P.S., Hauser L., Jetten M.S., Klotz M.G., Larimer F.W., Norton J.M., Op den Camp H.J.M., Shin M., Wei X.
    Environ. Microbiol. 9:2993-3007(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C91.

Entry informationi

Entry nameiSYL_NITEC
AccessioniPrimary (citable) accession number: Q0AG57
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 17, 2006
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3