UniProtKB - Q0AFN4 (SYR_NITEC)
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Protein
Arginine--tRNA ligase
Gene
argS
Organism
Nitrosomonas eutropha (strain C91)
Status
Functioni
Catalytic activityi
ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation
GO - Molecular functioni
- arginine-tRNA ligase activity Source: UniProtKB-EC
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- arginyl-tRNA aminoacylation Source: InterPro
Keywordsi
Molecular function | Aminoacyl-tRNA synthetase, Ligase |
Biological process | Protein biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)Alternative name(s): Arginyl-tRNA synthetaseUniRule annotation Short name: ArgRSUniRule annotation |
Gene namesi | Name:argSUniRule annotation Ordered Locus Names:Neut_1605 |
Organismi | Nitrosomonas eutropha (strain C91) |
Taxonomic identifieri | 335283 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Nitrosomonadaceae › Nitrosomonas › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000018076 | 1 – 586 | Arginine--tRNA ligaseAdd BLAST | 586 |
Interactioni
Subunit structurei
Monomer.UniRule annotation
Protein-protein interaction databases
STRINGi | 335283.Neut_1605. |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 131 – 141 | "HIGH" regionAdd BLAST | 11 |
Sequence similaritiesi
Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG4105C75. Bacteria. COG0018. LUCA. |
HOGENOMi | HOG000247214. |
KOi | K01887. |
OMAi | NKPLHLG. |
OrthoDBi | POG091H01RF. |
Family and domain databases
CDDi | cd00671. ArgRS_core. 1 hit. |
Gene3Di | 3.30.1360.70. 1 hit. |
HAMAPi | MF_00123. Arg_tRNA_synth. 1 hit. |
InterProi | View protein in InterPro IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase. IPR005148. Arg-tRNA-synth_N. IPR036695. Arg-tRNA-synth_N_sf. IPR035684. ArgRS_core. IPR008909. DALR_anticod-bd. IPR009080. tRNAsynth_Ia_anticodon-bd. |
PANTHERi | PTHR11956. PTHR11956. 1 hit. |
Pfami | View protein in Pfam PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 2 hits. |
PRINTSi | PR01038. TRNASYNTHARG. |
SMARTi | View protein in SMART SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. |
SUPFAMi | SSF47323. SSF47323. 1 hit. SSF55190. SSF55190. 1 hit. |
TIGRFAMsi | TIGR00456. argS. 1 hit. |
PROSITEi | View protein in PROSITE PS00178. AA_TRNA_LIGASE_I. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q0AFN4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATTIPFDFR SHCVQLLAQA VKQVLPEETE IHIELQRPKQ MDHGDYSTNL
60 70 80 90 100
AMKLAKRLRR NPLELAKVLI GALPDSPYVG KTVVAGGGFV NFFLKKTAKQ
110 120 130 140 150
QFLLTVLQAA DSFGHSKLGA GKTIQIEFVS ANPTGPLHVG HGRGAAFGAS
160 170 180 190 200
LANIMAAAGY AVTREFYVND AGRQMDILAL STWLRYLDLC GIALPFPSNA
210 220 230 240 250
YQGRYVVDMA LEIHRIHGDR YAHYSDSPTQ QLAEINAKAA ADGEDEYLDN
260 270 280 290 300
LITAAKSILG EDYAYLHNFV LTEQLNDCRN DLMEFGVEFE NWFSEQSLFD
310 320 330 340 350
SGMVARAVQL LDDKKLLYRQ DGALWFQSTG FGDEKDRVVQ RENGQYTYFA
360 370 380 390 400
SDIAYHLSKY ERGFDYMLNI WGADHHGYIS RVKGAIEALS LDSDKLEIAL
410 420 430 440 450
VQFAVLYRDG NKISMSTRSG EFVTLRQLRQ EVGNDAARFF YVLRKSDQHL
460 470 480 490 500
DFDLDLAKSQ SNDNPVYYVQ YAHARICSVL EQWGGAVDIF GRAETELLTN
510 520 530 540 550
PAELVLLQKI IDFPDTIEAA AKEHAPHLIA FFLRELASEF HSYYNSTRFL
560 570 580
IPDEALKIAR LALISAVCQV LSKGLSLLGV TSPRKM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000450 Genomic DNA. Translation: ABI59848.1. |
RefSeqi | WP_011634654.1. NC_008344.1. |
Genome annotation databases
EnsemblBacteriai | ABI59848; ABI59848; Neut_1605. |
KEGGi | net:Neut_1605. |
Similar proteinsi
Entry informationi
Entry namei | SYR_NITEC | |
Accessioni | Q0AFN4Primary (citable) accession number: Q0AFN4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 15, 2008 |
Last sequence update: | October 17, 2006 | |
Last modified: | February 28, 2018 | |
This is version 79 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |