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UniProtKB - Q0AFN4 (SYR_NITEC)

UniProt

Q0AFN4 - SYR_NITEC

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Nitrosomonas eutropha (strain C91)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNEUT335283:GHT6-1636-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Neut_1605
OrganismiNitrosomonas eutropha (strain C91)
Taxonomic identifieri335283 [NCBI]
Taxonomic lineageiBacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Nitrosomonadaceae › Nitrosomonas ›
Proteomesi
  • UP000001966 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 586586Arginine--tRNA ligasePRO_1000018076Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi335283.Neut_1605.

Structurei

3D structure databases

ProteinModelPortaliQ0AFN4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi131 – 14111"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247214.
KOiK01887.
OMAiHVGHIRN.
OrthoDBiPOG091H01RF.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 2 hits.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0AFN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTIPFDFR SHCVQLLAQA VKQVLPEETE IHIELQRPKQ MDHGDYSTNL 
        60         70         80         90        100
AMKLAKRLRR NPLELAKVLI GALPDSPYVG KTVVAGGGFV NFFLKKTAKQ 
       110        120        130        140        150
QFLLTVLQAA DSFGHSKLGA GKTIQIEFVS ANPTGPLHVG HGRGAAFGAS 
       160        170        180        190        200
LANIMAAAGY AVTREFYVND AGRQMDILAL STWLRYLDLC GIALPFPSNA 
       210        220        230        240        250
YQGRYVVDMA LEIHRIHGDR YAHYSDSPTQ QLAEINAKAA ADGEDEYLDN 
       260        270        280        290        300
LITAAKSILG EDYAYLHNFV LTEQLNDCRN DLMEFGVEFE NWFSEQSLFD 
       310        320        330        340        350
SGMVARAVQL LDDKKLLYRQ DGALWFQSTG FGDEKDRVVQ RENGQYTYFA 
       360        370        380        390        400
SDIAYHLSKY ERGFDYMLNI WGADHHGYIS RVKGAIEALS LDSDKLEIAL 
       410        420        430        440        450
VQFAVLYRDG NKISMSTRSG EFVTLRQLRQ EVGNDAARFF YVLRKSDQHL 
       460        470        480        490        500
DFDLDLAKSQ SNDNPVYYVQ YAHARICSVL EQWGGAVDIF GRAETELLTN 
       510        520        530        540        550
PAELVLLQKI IDFPDTIEAA AKEHAPHLIA FFLRELASEF HSYYNSTRFL 
       560        570        580 
IPDEALKIAR LALISAVCQV LSKGLSLLGV TSPRKM
Length:586
Mass (Da):65,632
Last modified:October 17, 2006 - v1
Checksum:iBA3B6F4517BEB060
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000450 Genomic DNA. Translation: ABI59848.1.
RefSeqiWP_011634654.1. NC_008344.1.

Genome annotation databases

EnsemblBacteriaiABI59848; ABI59848; Neut_1605.
KEGGinet:Neut_1605.
PATRICi22720628. VBINitEut7577_1969.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000450 Genomic DNA. Translation: ABI59848.1.
RefSeqiWP_011634654.1. NC_008344.1.

3D structure databases

ProteinModelPortaliQ0AFN4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi335283.Neut_1605.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABI59848; ABI59848; Neut_1605.
KEGGinet:Neut_1605.
PATRICi22720628. VBINitEut7577_1969.

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247214.
KOiK01887.
OMAiHVGHIRN.
OrthoDBiPOG091H01RF.

Enzyme and pathway databases

BioCyciNEUT335283:GHT6-1636-MONOMER.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 2 hits.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSYR_NITEC
AccessioniPrimary (citable) accession number: Q0AFN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 17, 2006
Last modified: September 7, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.