ID   HEM6_NITEC              Reviewed;         301 AA.
AC   Q0AEP6;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Coproporphyrinogen-III oxidase, aerobic;
DE            Short=Coproporphyrinogenase;
DE            Short=Coprogen oxidase;
DE            EC=1.3.3.3;
GN   Name=hemF; OrderedLocusNames=Neut_1956;
OS   Nitrosomonas eutropha (strain C91).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=335283;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17991028; DOI=10.1111/j.1462-2920.2007.01409.x;
RA   Stein L.Y., Arp D.J., Berube P.M., Chain P.S., Hauser L., Jetten M.S.,
RA   Klotz M.G., Larimer F.W., Norton J.M., Op den Camp H.J.M., Shin M.,
RA   Wei X.;
RT   "Whole-genome analysis of the ammonia-oxidizing bacterium,
RT   Nitrosomonas eutropha C91: implications for niche adaptation.";
RL   Environ. Microbiol. 9:2993-3007(2007).
CC   -!- CATALYTIC ACTIVITY: Coproporphyrinogen-III + O(2) + 2 H(+) =
CC       protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
CC   -!- PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis;
CC       protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step
CC       1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the aerobic coproporphyrinogen-III oxidase
CC       family.
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DR   EMBL; CP000450; ABI60186.1; -; Genomic_DNA.
DR   RefSeq; YP_748151.1; -.
DR   GeneID; 4273308; -.
DR   GenomeReviews; CP000450_GR; Neut_1956.
DR   KEGG; net:Neut_1956; -.
DR   NMPDR; fig|335283.3.peg.1081; -.
DR   OMA; Q0AEP6; VKAYLLD.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004109; F:coproporphyrinogen oxidase activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006779; P:porphyrin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00333; -; 1.
DR   InterPro; IPR001260; Coprogen_oxidas.
DR   InterPro; IPR018375; Coproporphyrinogen-3_ox_CS.
DR   Gene3D; G3DSA:3.40.1500.10; Coprogen_oxidas; 1.
DR   PANTHER; PTHR10755; Coprogen_oxidas; 1.
DR   Pfam; PF01218; Coprogen_oxidas; 1.
DR   PIRSF; PIRSF000166; Coproporphyri_ox; 1.
DR   PRINTS; PR00073; COPRGNOXDASE.
DR   PROSITE; PS01021; COPROGEN_OXIDASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Oxidoreductase; Porphyrin biosynthesis.
FT   CHAIN         1    301       Coproporphyrinogen-III oxidase, aerobic.
FT                                /FTId=PRO_1000019473.
SQ   SEQUENCE   301 AA;  34003 MW;  6C297DF69EA1825D CRC64;
     MDFAQVKDYL VNLQNNIVAG LEQADGGSFR RDSWDRPEGG GGTSCVIEEG NVLERGGVNF
     SHVHGKGLPA SATAARPELA GRAFEAAGVS LVLHPRNPYA PTVHMNVRFF AAIKEGAEPV
     WWFGGGMDLT PYYGFEEDAI HFHQICKHAL QPSGSEYYPR FKKWCDEYFY LKHRKEPRGI
     GGVFFDDLNQ PDFVTCFNLT KSVGDQFLAA YVPILQKRCN LPYGERERDF QAYRRGRYVE
     FNLVWDRGTL FGLQSGGRTE SILMSLPPIV KWRYDWSPAA GSPEAKLYTD FLIGKDWLPL
     D
//