ID   DAPF_ALHEH              Reviewed;         279 AA.
AC   Q0ACL9;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Diaminopimelate epimerase;
DE            Short=DAP epimerase;
DE            EC=5.1.1.7;
GN   Name=dapF; OrderedLocusNames=Mlg_0061;
OS   Alkalilimnicola ehrlichei (strain MLHE-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Alkalilimnicola.
OX   NCBI_TaxID=187272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Oremland R.S., Hoeft S.E., Switzer-Blum J., Kulp T.,
RA   King G., Tabita R., Witte B., Santini J.M., Basu P., Hollibaugh J.T.,
RA   Xie G., Stolz J.F., Richardson P.;
RT   "Complete sequence of Alkalilimnicola ehrilichei MLHE-1.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: LL-2,6-diaminoheptanedioate = meso-
CC       diaminoheptanedioate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; DL-diaminopimelate from LL-diaminopimelate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the diaminopimelate epimerase family.
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DR   EMBL; CP000453; ABI55418.1; -; Genomic_DNA.
DR   RefSeq; YP_740908.1; -.
DR   GeneID; 4270339; -.
DR   GenomeReviews; CP000453_GR; Mlg_0061.
DR   KEGG; aeh:Mlg_0061; -.
DR   NMPDR; fig|187272.6.peg.57; -.
DR   HOGENOM; Q0ACL9; -.
DR   OMA; Q0ACL9; PHAVLRV.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008837; F:diaminopimelate epimerase activity; IEA:HAMAP.
DR   GO; GO:0009089; P:lysine biosynthetic process via diaminopime...; IEA:HAMAP.
DR   HAMAP; MF_00197; -; 1.
DR   InterPro; IPR001653; DAP_epimerase.
DR   InterPro; IPR018510; DAP_epimerase_CS.
DR   Pfam; PF01678; DAP_epimerase; 2.
DR   TIGRFAMs; TIGR00652; DapF; 1.
DR   PROSITE; PS01326; DAP_EPIMERASE; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Lysine biosynthesis.
FT   CHAIN         1    279       Diaminopimelate epimerase.
FT                                /FTId=PRO_1000011832.
FT   ACT_SITE     75     75       By similarity.
FT   ACT_SITE    221    221       By similarity.
SQ   SEQUENCE   279 AA;  30481 MW;  864915CA9A0E9EFF CRC64;
     MKVRFTKMQG LGNDFVVIDA VRQPVEPSPE QIRHIADRRY GVGCDQVLLA TPARRSQADF
     GYLIFNPDGS QAEHCGNGVR CLARFLDDRG LVPAGRHELV IETINGLSRV RLCDDGPVTV
     DMGAPVLEPP HIPFRAPSRA REYELEVEGQ VVRLGAVSMG NPHAVLRVDD VDSAPVETLG
     PAIESHSRFP RRVNVGFMQV LTPTHIRLRV YERGAGETLA CGTGACAAVV SGRLRGWLEE
     AVDVDLPGGR LVIHWAGDGE HVWMTGPAET VFEGEIRLD
//