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Q0ACL9 (DAPF_ALHEH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7
Gene names
Name:dapF
Ordered Locus Names:Mlg_0061
OrganismAlkalilimnicola ehrlichei (strain MLHE-1) [Complete proteome] [HAMAP]
Taxonomic identifier187272 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Ectothiorhodospiraceae › Alkalilimnicola

Protein attributes

Sequence length279 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 279279Diaminopimelate epimerase HAMAP MF_00197
PRO_1000011832

Sites

Active site751 By similarity
Active site2211 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0ACL9 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 864915CA9A0E9EFF

FASTA27930,481
        10         20         30         40         50         60 
MKVRFTKMQG LGNDFVVIDA VRQPVEPSPE QIRHIADRRY GVGCDQVLLA TPARRSQADF 

        70         80         90        100        110        120 
GYLIFNPDGS QAEHCGNGVR CLARFLDDRG LVPAGRHELV IETINGLSRV RLCDDGPVTV 

       130        140        150        160        170        180 
DMGAPVLEPP HIPFRAPSRA REYELEVEGQ VVRLGAVSMG NPHAVLRVDD VDSAPVETLG 

       190        200        210        220        230        240 
PAIESHSRFP RRVNVGFMQV LTPTHIRLRV YERGAGETLA CGTGACAAVV SGRLRGWLEE 

       250        260        270 
AVDVDLPGGR LVIHWAGDGE HVWMTGPAET VFEGEIRLD

« Hide

References

[1]"Complete sequence of Alkalilimnicola ehrilichei MLHE-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Oremland R.S., Hoeft S.E., Switzer-Blum J., Kulp T., King G., Tabita R., Witte B., Santini J.M., Basu P., Hollibaugh J.T., Xie G., Stolz J.F., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MLHE-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000453 Genomic DNA. Translation: ABI55418.1.
RefSeqYP_740908.1. NC_008340.1.

3D structure databases

ProteinModelPortalQ0ACL9.
SMRQ0ACL9. Positions 3-278.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0ACL9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4270339.
GenomeReviewsGene locus Mlg_0061 in contig CP000453_GR.
KEGGaeh:Mlg_0061.
NMPDRfig|187272.6.peg.57.
PATRIC20859294. VBIAlkEhr114327_0062.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0253.
HOGENOMHBG399442.
OMAFMTGPAT.
PhylomeDBQ0ACL9.
ProtClustDBPRK00450.

Enzyme and pathway databases

BioCycAEHR187272:MLG_0061-MONOMER.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPF_ALHEH
AccessionPrimary (citable) accession number: Q0ACL9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 17, 2006
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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