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Protein

Urease subunit beta

Gene

ureB

Organism
Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Urea + H2O = CO2 + 2 NH3.UniRule annotation

Pathwayi: urea degradation

This protein is involved in step 1 of the subpathway that synthesizes CO(2) and NH(3) from urea (urease route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Urease subunit beta (ureB), Urease subunit gamma (ureA), Urease subunit alpha (ureC)
This subpathway is part of the pathway urea degradation, which is itself part of Nitrogen metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CO(2) and NH(3) from urea (urease route), the pathway urea degradation and in Nitrogen metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciAEHR187272:GHAX-183-MONOMER.
UniPathwayiUPA00258; UER00370.

Names & Taxonomyi

Protein namesi
Recommended name:
Urease subunit betaUniRule annotation (EC:3.5.1.5UniRule annotation)
Alternative name(s):
Urea amidohydrolase subunit betaUniRule annotation
Gene namesi
Name:ureBUniRule annotation
Ordered Locus Names:Mlg_0183
OrganismiAlkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Taxonomic identifieri187272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeAlkalilimnicola
Proteomesi
  • UP000001962 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 106106Urease subunit betaPRO_1000070712Add
BLAST

Interactioni

Subunit structurei

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.UniRule annotation

Protein-protein interaction databases

STRINGi187272.Mlg_0183.

Structurei

3D structure databases

ProteinModelPortaliQ0AC99.
SMRiQ0AC99. Positions 1-100.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the urease beta subunit family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105KI2. Bacteria.
COG0832. LUCA.
HOGENOMiHOG000077770.
KOiK01429.
OMAiREVYGFQ.
OrthoDBiEOG69PQ9G.

Family and domain databases

Gene3Di2.10.150.10. 1 hit.
HAMAPiMF_01954. Urease_beta.
InterProiIPR002019. Urease_beta.
[Graphical view]
PfamiPF00699. Urease_beta. 1 hit.
[Graphical view]
SUPFAMiSSF51278. SSF51278. 1 hit.
TIGRFAMsiTIGR00192. urease_beta. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0AC99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPGEILPED GEITLNAGRD TLTVEVTNTG DRPAQVGSHY HFYEVNDHLH
60 70 80 90 100
FDREPTRGFR LDIAAGTAVR FEPGQSRTVQ LVRYAGSGDI YGFQGRVMGP

ATGESA
Length:106
Mass (Da):11,563
Last modified:October 17, 2006 - v1
Checksum:iBB1F2FCF0F1DC9D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000453 Genomic DNA. Translation: ABI55538.1.
RefSeqiWP_011627934.1. NC_008340.1.

Genome annotation databases

EnsemblBacteriaiABI55538; ABI55538; Mlg_0183.
KEGGiaeh:Mlg_0183.
PATRICi20859524. VBIAlkEhr114327_0176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000453 Genomic DNA. Translation: ABI55538.1.
RefSeqiWP_011627934.1. NC_008340.1.

3D structure databases

ProteinModelPortaliQ0AC99.
SMRiQ0AC99. Positions 1-100.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187272.Mlg_0183.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABI55538; ABI55538; Mlg_0183.
KEGGiaeh:Mlg_0183.
PATRICi20859524. VBIAlkEhr114327_0176.

Phylogenomic databases

eggNOGiENOG4105KI2. Bacteria.
COG0832. LUCA.
HOGENOMiHOG000077770.
KOiK01429.
OMAiREVYGFQ.
OrthoDBiEOG69PQ9G.

Enzyme and pathway databases

UniPathwayiUPA00258; UER00370.
BioCyciAEHR187272:GHAX-183-MONOMER.

Family and domain databases

Gene3Di2.10.150.10. 1 hit.
HAMAPiMF_01954. Urease_beta.
InterProiIPR002019. Urease_beta.
[Graphical view]
PfamiPF00699. Urease_beta. 1 hit.
[Graphical view]
SUPFAMiSSF51278. SSF51278. 1 hit.
TIGRFAMsiTIGR00192. urease_beta. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1101 / DSM 17681 / MLHE-1.

Entry informationi

Entry nameiURE2_ALKEH
AccessioniPrimary (citable) accession number: Q0AC99
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 17, 2006
Last modified: December 9, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.