Reviewed, UniProtKB/Swiss-Prot Q0AAC1 (PSD_ALHEH)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	Mlg_0862

Organism

Alkalilimnicola ehrlichei (strain MLHE-1) [Complete proteome] [HAMAP]

Taxonomic identifier

187272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Ectothiorhodospiraceae › Alkalilimnicola

Protein attributes

Sequence length	288 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662
Cofactor	Pyruvoyl group By similarity. HAMAP MF_00662
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 261	261	Phosphatidylserine decarboxylase beta chain By similarity		PRO_0000262091
	Chain	262 – 288	27	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_0000262092
Sites
	Site	261 – 262	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	262	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0AAC1-1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 779E23DA3A9BE5CC	FASTA	288	31,988
	10 20 30 40 50 60 MSVYRDESPA TGLDHLKAAL LYPLPHHAIS RMVHWAVRVE TPWFKNLLIK AFIRVFKVDM 70 80 90 100 110 120 SEALEEDPTA YPTFNAFFTR ALKPEARPLP DDPDAILSPA DGTISQMGPI ERDTIFQAKG 130 140 150 160 170 180 HSFTTAELLG GDEALAEEFR DGWFATIYLS PRDYHRVHMP MTGTLRQMIH IPGRLFSVAP 190 200 210 220 230 240 FTVRTVPKLF ARNERVACIF DTDRGPMAVV LVGAINVGSI ETVWAGEITP PAGIRAQYSN 250 260 270 280 YEADNAPTIA RGHEMGRFNM GSTVITLQNS RPAPGKIMSA HIKQGMTI

References

[1]

"Complete sequence of Alkalilimnicola ehrilichei MLHE-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Oremland R.S., Hoeft S.E., Switzer-Blum J., Kulp T., King G., Tabita R., Witte B., Santini J.M., Basu P., Hollibaugh J.T., Xie G., Stolz J.F., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000453 Genomic DNA. Translation: ABI56216.1.
RefSeq	YP_741706.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0AAC1.
Genome annotation databases
GeneID	4268506.
GenomeReviews	Gene locus Mlg_0862 in contig CP000453_GR.
KEGG	aeh:Mlg_0862.
NMPDR	fig|187272.6.peg.831.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0688.
HOGENOM	HBG302256.
OMA	YVPGRLF.
PhylomeDB	Q0AAC1.
Family and domain databases
HAMAP	MF_00662. PS_decarb_type1. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR005221. PS_decarb. [Graphical view]
PANTHER	PTHR10067. PS_decarb. 1 hit.
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00163. PS_decarb. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_ALHEH

Accession

Primary (citable) accession number: Q0AAC1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	October 17, 2006
Last modified:	February 9, 2010
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)