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Q0AA26

- GLGB_ALKEH

UniProt

Q0AA26 - GLGB_ALKEH

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Protein
1,4-alpha-glucan branching enzyme GlgB
Gene
glgB, Mlg_0958
Organism
Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei368 – 3681Nucleophile By similarity
Active sitei421 – 4211Proton donor By similarity

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciAEHR187272:GHAX-987-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgB (EC:2.4.1.18)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name:
BE
Gene namesi
Name:glgB
Ordered Locus Names:Mlg_0958
OrganismiAlkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Taxonomic identifieri187272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeAlkalilimnicola
ProteomesiUP000001962: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6956951,4-alpha-glucan branching enzyme GlgBUniRule annotation
PRO_0000260635Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi187272.Mlg_0958.

Structurei

3D structure databases

ProteinModelPortaliQ0AA26.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000283037.
KOiK00700.
OrthoDBiEOG6JX7GT.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0AA26-1 [UniParc]FASTAAdd to Basket

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MRVYDPHAEA VAFEDGTKLP RRPGSDFFEG PLPAGLSAPY RLRRTSQDGA    50
AHTAHDPYAF GPALPDYDLH LFGEGRHYHA QRFLGAHPLE HEGVPGVRFA 100
VWAPNAERVS VVGDFNRWDG RCHPMRVRGG SGVWELFIPG LPDGSLYKFE 150
LRNRDSGAVL VKTDPYGRRY QLRPDSAAVV EPPADYAWND REWMAARRED 200
QWQSIPISIY EVHLGSWQRA GDGSFLDYRT LAHRLVDHVL ATGFTHIELL 250
PITEHPFDGS WGYQTTGYFA PTTRFGAPDD FRYFVDHCHR HGIGVILDWV 300
PAHFPRDDWA LANFDGTPLY EHADPRRGEH RDWGTLIFNF GRNEVRNFLT 350
ASALYWLEEF HIDGLRVDAV ASMLYLDYSR DEGDWVPNIH GGNENLEAID 400
FLQELNRITH GEQPGTMIMA EESTSWPQVT RPTWLGGLGF TMKWNMGWMH 450
DTLTYMGEDP IHRRYHHDQL TFGMLYAFTE NFVLPFSHDE VVHGKRSLLW 500
RMPGDEWQRF ANLRLLYAYQ FTYPGKKLLF MGCEFGQGNE WNAEAALDWY 550
VLDYPLHQGV LRLVGDLNAL YREVPALHRH DFDEHGFAWI DCHDTEQSAI 600
SYLRRDGGHD GEATPPAATV LNFTPVPRHD YRLGVPAPGY WRERLNTDST 650
HYGGTNLGNG GGVWAEAVPW MGHPWSVVLT LPPLAGVVLS PEAGP 695
Length:695
Mass (Da):79,236
Last modified:October 17, 2006 - v1
Checksum:iAB4E1FFDFF96037F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000453 Genomic DNA. Translation: ABI56311.1.
RefSeqiYP_741801.1. NC_008340.1.

Genome annotation databases

EnsemblBacteriaiABI56311; ABI56311; Mlg_0958.
GeneIDi4270428.
KEGGiaeh:Mlg_0958.
PATRICi20861143. VBIAlkEhr114327_0956.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000453 Genomic DNA. Translation: ABI56311.1 .
RefSeqi YP_741801.1. NC_008340.1.

3D structure databases

ProteinModelPortali Q0AA26.
ModBasei Search...

Protein-protein interaction databases

STRINGi 187272.Mlg_0958.

Protein family/group databases

CAZyi CBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI56311 ; ABI56311 ; Mlg_0958 .
GeneIDi 4270428.
KEGGi aeh:Mlg_0958.
PATRICi 20861143. VBIAlkEhr114327_0956.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000283037.
KOi K00700.
OrthoDBi EOG6JX7GT.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci AEHR187272:GHAX-987-MONOMER.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_00685. GlgB.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1101 / DSM 17681 / MLHE-1.

Entry informationi

Entry nameiGLGB_ALKEH
AccessioniPrimary (citable) accession number: Q0AA26
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: October 17, 2006
Last modified: June 11, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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