Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sulfate adenylyltransferase subunit 2 2

Gene

cysD2

Organism
Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + sulfate = diphosphate + adenylyl sulfate.UniRule annotation

Pathwayi: hydrogen sulfide biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes sulfite from sulfate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Sulfate adenylyltransferase subunit 1 (Mlg_1260), Sulfate adenylyltransferase subunit 2 2 (cysD2), Sulfate adenylyltransferase subunit 2 1 (cysD1)
  2. no protein annotated in this organism
  3. Phosphoadenosine phosphosulfate reductase (cysH), Phosphoadenylylsulfate reductase (Thioredoxin) (Mlg_1263)
This subpathway is part of the pathway hydrogen sulfide biosynthesis, which is itself part of Sulfur metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes sulfite from sulfate, the pathway hydrogen sulfide biosynthesis and in Sulfur metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAEHR187272:GHAX-2396-MONOMER.
UniPathwayiUPA00140; UER00204.

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfate adenylyltransferase subunit 2 2UniRule annotation (EC:2.7.7.4UniRule annotation)
Alternative name(s):
ATP-sulfurylase small subunit 2UniRule annotation
Sulfate adenylate transferase 2UniRule annotation
Short name:
SAT 2UniRule annotation
Gene namesi
Name:cysD2UniRule annotation
Ordered Locus Names:Mlg_2344
OrganismiAlkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Taxonomic identifieri187272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeAlkalilimnicola
Proteomesi
  • UP000001962 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302Sulfate adenylyltransferase subunit 2 2PRO_0000340176Add
BLAST

Proteomic databases

PRIDEiQ0A653.

Interactioni

Subunit structurei

Heterodimer composed of CysD, the smaller subunit, and CysN.UniRule annotation

Protein-protein interaction databases

STRINGi187272.Mlg_2344.

Structurei

3D structure databases

ProteinModelPortaliQ0A653.
SMRiQ0A653. Positions 6-212.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PAPS reductase family. CysD subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C11. Bacteria.
COG0175. LUCA.
HOGENOMiHOG000263604.
KOiK00957.
OMAiQSASMEK.
OrthoDBiPOG091H03PV.

Family and domain databases

Gene3Di3.40.50.620. 2 hits.
HAMAPiMF_00064. Sulf_adenylyltr_sub2. 1 hit.
InterProiIPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
IPR011784. SO4_adenylTrfase_ssu.
[Graphical view]
PfamiPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFiPIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMsiTIGR02039. CysD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0A653-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNRTLTHLR QLEAESIHII REVVAEFENP VMLYSIGKDS SVMLHLARKA
60 70 80 90 100
FYPGTPPFPL MHVDTTWKFR EMIEFRDRMA KEAGMELIVH INQEGVAQGI
110 120 130 140 150
GPFSHGSRVH TDVMKTQSLK QALDKYRFDA AFGGARRDEE RSRAKERVYS
160 170 180 190 200
FRDRNHAWDP KNQRPELWRL YNGQVHKGES IRVFPLSNWT ELDIWQYIYL
210 220 230 240 250
EEIPIVPLYY AARRPVVERD GTLIMVDDDR MPLEPGEEPE MAMVRFRTLG
260 270 280 290 300
CYPLTGAIRS EAATLPEIIQ EMLLTKSSER QGRVIDHDAA GSMEEKKRQG

YF
Length:302
Mass (Da):35,141
Last modified:October 17, 2006 - v1
Checksum:i981C33BA9F957E8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000453 Genomic DNA. Translation: ABI57684.1.
RefSeqiWP_011630077.1. NC_008340.1.

Genome annotation databases

EnsemblBacteriaiABI57684; ABI57684; Mlg_2344.
KEGGiaeh:Mlg_2344.
PATRICi20863937. VBIAlkEhr114327_2333.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000453 Genomic DNA. Translation: ABI57684.1.
RefSeqiWP_011630077.1. NC_008340.1.

3D structure databases

ProteinModelPortaliQ0A653.
SMRiQ0A653. Positions 6-212.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187272.Mlg_2344.

Proteomic databases

PRIDEiQ0A653.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABI57684; ABI57684; Mlg_2344.
KEGGiaeh:Mlg_2344.
PATRICi20863937. VBIAlkEhr114327_2333.

Phylogenomic databases

eggNOGiENOG4105C11. Bacteria.
COG0175. LUCA.
HOGENOMiHOG000263604.
KOiK00957.
OMAiQSASMEK.
OrthoDBiPOG091H03PV.

Enzyme and pathway databases

UniPathwayiUPA00140; UER00204.
BioCyciAEHR187272:GHAX-2396-MONOMER.

Family and domain databases

Gene3Di3.40.50.620. 2 hits.
HAMAPiMF_00064. Sulf_adenylyltr_sub2. 1 hit.
InterProiIPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
IPR011784. SO4_adenylTrfase_ssu.
[Graphical view]
PfamiPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFiPIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMsiTIGR02039. CysD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCYSD2_ALKEH
AccessioniPrimary (citable) accession number: Q0A653
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: October 17, 2006
Last modified: September 7, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.