Q0A653 (CYSD2_ALHEH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit 2
Sulfate adenylate transferase 2
Short name=SAT 2

Gene names

Name:	cysD2
Ordered Locus Names:	Mlg_2344

Organism

Alkalilimnicola ehrlichei (strain MLHE-1) [Complete proteome] [HAMAP]

Taxonomic identifier

187272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Ectothiorhodospiraceae › Alkalilimnicola

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	Sulfate adenylyltransferase subunit 2 2 HAMAP MF_00064		PRO_0000340176

Sequences

	Sequence		Length	Mass (Da)
	Q0A653 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 981C33BA9F957E8A	FASTA	302	35,141
	10 20 30 40 50 60 MDNRTLTHLR QLEAESIHII REVVAEFENP VMLYSIGKDS SVMLHLARKA FYPGTPPFPL 70 80 90 100 110 120 MHVDTTWKFR EMIEFRDRMA KEAGMELIVH INQEGVAQGI GPFSHGSRVH TDVMKTQSLK 130 140 150 160 170 180 QALDKYRFDA AFGGARRDEE RSRAKERVYS FRDRNHAWDP KNQRPELWRL YNGQVHKGES 190 200 210 220 230 240 IRVFPLSNWT ELDIWQYIYL EEIPIVPLYY AARRPVVERD GTLIMVDDDR MPLEPGEEPE 250 260 270 280 290 300 MAMVRFRTLG CYPLTGAIRS EAATLPEIIQ EMLLTKSSER QGRVIDHDAA GSMEEKKRQG YF

References

[1]

"Complete sequence of Alkalilimnicola ehrilichei MLHE-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Oremland R.S., Hoeft S.E., Switzer-Blum J., Kulp T., King G., Tabita R., Witte B., Santini J.M., Basu P., Hollibaugh J.T., Xie G., Stolz J.F., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MLHE-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000453 Genomic DNA. Translation: ABI57684.1.
RefSeq	YP_743174.1. NC_008340.1.
3D structure databases
ProteinModelPortal	Q0A653.
SMR	Q0A653. Positions 6-212.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0A653.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4269100.
GenomeReviews	Gene locus Mlg_2344 in contig CP000453_GR.
KEGG	aeh:Mlg_2344.
NMPDR	fig|187272.6.peg.2228.
PATRIC	20863937. VBIAlkEhr114327_2333.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	RVIDHDA.
PhylomeDB	Q0A653.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	AEHR187272:MLG_2344-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD2_ALHEH

Accession

Primary (citable) accession number: Q0A653

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	October 17, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program