ID   ABAH1_ORYSI             Reviewed;         471 AA.
AC   Q09J79;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   24-MAR-2009, entry version 19.
DE   RecName: Full=Abscisic acid 8'-hydroxylase 1;
DE            Short=ABA 8'-hydroxylase 1;
DE            EC=1.14.13.93;
DE   AltName: Full=OsABA8ox1;
DE   AltName: Full=Cytochrome P450 707A5;
GN   Name=CYP707A5; Synonyms=ABA8OX1; ORFNames=OsI_008437;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Ehrhartoideae; Oryzeae; Oryza.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, AND
RP   INDUCTION.
RC   STRAIN=cv. Pin Gaew 56;
RX   PubMed=17022939; DOI=10.1016/j.bbrc.2006.09.098;
RA   Yang S.-H., Choi D.;
RT   "Characterization of genes encoding ABA 8'-hydroxylase in ethylene-
RT   induced stem growth of deepwater rice (Oryza sativa L.).";
RL   Biochem. Biophys. Res. Commun. 350:685-690(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H.,
RA   Cong L., Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J.,
RA   Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X.,
RA   Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y.,
RA   Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J.,
RA   Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y.,
RA   Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y.,
RA   Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z.,
RA   Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T.,
RA   Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA   Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA   Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA   Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J.,
RA   Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Involved in the oxidative degradation of abscisic acid.
CC   -!- CATALYTIC ACTIVITY: (+)-abscisate + NADPH + O(2) = 8'-
CC       hydroxyabscisate + NADP(+) + H(2)O.
CC   -!- COFACTOR: Heme group (By similarity).
CC   -!- PATHWAY: Plant hormone degradation; abscisic acid degradation.
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein
CC       (Potential).
CC   -!- TISSUE SPECIFICITY: In seedlings and expanding leaves.
CC   -!- INDUCTION: By ethylene or abscisic acid treatments, and salt or
CC       osmotic stresses.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
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DR   EMBL; DQ887714; ABI64254.1; -; mRNA.
DR   EMBL; CM000127; EAY87204.1; -; Genomic_DNA.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017973; Cyt_P450_C.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   Gene3D; G3DSA:1.10.630.10; Cyt_P450; 1.
DR   PANTHER; PTHR19383; Cyt_P450; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Membrane; Metal-binding; Monooxygenase; NADP;
KW   Oxidoreductase; Stress response; Transmembrane.
FT   CHAIN         1    471       Abscisic acid 8'-hydroxylase 1.
FT                                /FTId=PRO_0000288643.
FT   TRANSMEM      1     21       Potential.
FT   METAL       415    415       Iron (heme axial ligand) (By similarity).
SQ   SEQUENCE   471 AA;  52920 MW;  24D4FB1BC5A62BE9 CRC64;
     MGAFLLFVCV LAPFLLVCAV RGRRRQAGSS EAAACGLPLP PGSMGWPYVG ETFQLYSSKN
     PNVFFNKKRN KYGPIFKTHI LGCPCVMVSS PEAARFVLVT QAHLFKPTFP ASKERMLGPQ
     AIFFQQGDYH AHLRRIVSRA FSPESIRASV PAIEAIALRS LHSWDGQFVN TFQEMKTYAL
     NVALLSIFGE EEMRYIEELK QCYLTLEKGY NSMPVNLPGT LFHKAMKARK RLGAIVAHII
     SARRERQRGN DLLGSFVDGR EALTDAQIAD NVIGVIFAAR DTTASVLTWM VKFLGDHPAV
     LKAVTEEQLQ IAKEKEASGE PLSWADTRRM KMTSRVIQET MRVASILSFT FREAVEDVEY
     QGYLIPKGWK VLPLFRNIHH NPDHFPCPEK FDPSRFEVAP KPNTFMPFGN GTHSCPGNEL
     AKLEMLVLFH HLATKYRWST SKSESGVQFG PFALPLNGLP MSFTRKNTEQ E
//