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Protein

Abscisic acid 8'-hydroxylase 1

Gene

CYP707A5

Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the oxidative degradation of abscisic acid.1 Publication

Catalytic activityi

+-abscisate + NADPH + O2 = 8'-hydroxyabscisate + NADP+ + H2O.

Cofactori

hemeBy similarity

Pathwayi: abscisic acid degradation

This protein is involved in the pathway abscisic acid degradation, which is part of Plant hormone degradation.
View all proteins of this organism that are known to be involved in the pathway abscisic acid degradation and in Plant hormone degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi415Iron (heme axial ligand)By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Monooxygenase, Oxidoreductase

Keywords - Biological processi

Stress response

Keywords - Ligandi

Heme, Iron, Metal-binding, NADP

Enzyme and pathway databases

UniPathwayiUPA00093.

Names & Taxonomyi

Protein namesi
Recommended name:
Abscisic acid 8'-hydroxylase 1 (EC:1.14.13.93)
Short name:
ABA 8'-hydroxylase 1
Alternative name(s):
Cytochrome P450 707A5
OsABA8ox1
Gene namesi
Name:CYP707A5
Synonyms:ABA8OX1
ORF Names:OsI_008437
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000007015 Componenti: Chromosome 2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1 – 21HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002886431 – 471Abscisic acid 8'-hydroxylase 1Add BLAST471

Expressioni

Tissue specificityi

In seedlings and expanding leaves.1 Publication

Inductioni

By ethylene or abscisic acid treatments, and salt or osmotic stresses.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi39946.BGIOSGA008883-PA.

Structurei

3D structure databases

ProteinModelPortaliQ09J79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0157. Eukaryota.
COG2124. LUCA.
HOGENOMiHOG000237614.
OMAiFHHLATK.
OrthoDBiEOG093608YU.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09J79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAFLLFVCV LAPFLLVCAV RGRRRQAGSS EAAACGLPLP PGSMGWPYVG
60 70 80 90 100
ETFQLYSSKN PNVFFNKKRN KYGPIFKTHI LGCPCVMVSS PEAARFVLVT
110 120 130 140 150
QAHLFKPTFP ASKERMLGPQ AIFFQQGDYH AHLRRIVSRA FSPESIRASV
160 170 180 190 200
PAIEAIALRS LHSWDGQFVN TFQEMKTYAL NVALLSIFGE EEMRYIEELK
210 220 230 240 250
QCYLTLEKGY NSMPVNLPGT LFHKAMKARK RLGAIVAHII SARRERQRGN
260 270 280 290 300
DLLGSFVDGR EALTDAQIAD NVIGVIFAAR DTTASVLTWM VKFLGDHPAV
310 320 330 340 350
LKAVTEEQLQ IAKEKEASGE PLSWADTRRM KMTSRVIQET MRVASILSFT
360 370 380 390 400
FREAVEDVEY QGYLIPKGWK VLPLFRNIHH NPDHFPCPEK FDPSRFEVAP
410 420 430 440 450
KPNTFMPFGN GTHSCPGNEL AKLEMLVLFH HLATKYRWST SKSESGVQFG
460 470
PFALPLNGLP MSFTRKNTEQ E
Length:471
Mass (Da):52,920
Last modified:October 17, 2006 - v1
Checksum:i24D4FB1BC5A62BE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ887714 mRNA. Translation: ABI64254.1.
CM000127 Genomic DNA. Translation: EAY87204.1.

Genome annotation databases

EnsemblPlantsiBGIOSGA008883-TA; BGIOSGA008883-PA; BGIOSGA008883.
GrameneiBGIOSGA008883-TA; BGIOSGA008883-PA; BGIOSGA008883.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ887714 mRNA. Translation: ABI64254.1.
CM000127 Genomic DNA. Translation: EAY87204.1.

3D structure databases

ProteinModelPortaliQ09J79.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39946.BGIOSGA008883-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiBGIOSGA008883-TA; BGIOSGA008883-PA; BGIOSGA008883.
GrameneiBGIOSGA008883-TA; BGIOSGA008883-PA; BGIOSGA008883.

Phylogenomic databases

eggNOGiKOG0157. Eukaryota.
COG2124. LUCA.
HOGENOMiHOG000237614.
OMAiFHHLATK.
OrthoDBiEOG093608YU.

Enzyme and pathway databases

UniPathwayiUPA00093.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiABAH1_ORYSI
AccessioniPrimary (citable) accession number: Q09J79
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: October 17, 2006
Last modified: September 7, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.