Reviewed, UniProtKB/Swiss-Prot Q09J79 (ABAH1_ORYSI)

Names and origin

Protein names

Recommended name:
    Abscisic acid 8'-hydroxylase 1
      Short name=ABA 8'-hydroxylase 1
    EC=1.14.13.93
Alternative name(s):
    OsABA8ox1
    Cytochrome P450 707A5

Gene names

Name:	CYP707A5
Synonyms:	ABA8OX1
ORF Names:	OsI_008437

Organism

Oryza sativa subsp. indica (Rice)

Taxonomic identifier

39946 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	471 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Involved in the oxidative degradation of abscisic acid.
Catalytic activity	(+)-abscisate + NADPH + O(2) = 8'-hydroxyabscisate + NADP(+) + H(2)O.
Cofactor	Heme group By similarity.
Pathway	Plant hormone degradation; abscisic acid degradation.
Subcellular location	Membrane; Single-pass membrane proteinPotential.
Tissue specificity	In seedlings and expanding leaves.
Induction	By ethylene or abscisic acid treatments, and salt or osmotic stresses.
Sequence similarities	Belongs to the cytochrome P450 family.

Ontologies

Keywords
Biological process	Stress response
Cellular component	Membrane
Domain	Transmembrane
Ligand	Heme Iron Metal-binding NADP
Molecular function	Monooxygenase Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	(+)-abscisic acid 8'-hydroxylase activity Inferred from electronic annotation. Source: EC electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 471	471	Abscisic acid 8'-hydroxylase 1		PRO_0000288643
Regions
	Transmembrane	1 – 21	21	Potential
Sites
	Metal binding	415	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q09J79-1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 24D4FB1BC5A62BE9	FASTA	471	52,920
	10 20 30 40 50 60 MGAFLLFVCV LAPFLLVCAV RGRRRQAGSS EAAACGLPLP PGSMGWPYVG ETFQLYSSKN 70 80 90 100 110 120 PNVFFNKKRN KYGPIFKTHI LGCPCVMVSS PEAARFVLVT QAHLFKPTFP ASKERMLGPQ 130 140 150 160 170 180 AIFFQQGDYH AHLRRIVSRA FSPESIRASV PAIEAIALRS LHSWDGQFVN TFQEMKTYAL 190 200 210 220 230 240 NVALLSIFGE EEMRYIEELK QCYLTLEKGY NSMPVNLPGT LFHKAMKARK RLGAIVAHII 250 260 270 280 290 300 SARRERQRGN DLLGSFVDGR EALTDAQIAD NVIGVIFAAR DTTASVLTWM VKFLGDHPAV 310 320 330 340 350 360 LKAVTEEQLQ IAKEKEASGE PLSWADTRRM KMTSRVIQET MRVASILSFT FREAVEDVEY 370 380 390 400 410 420 QGYLIPKGWK VLPLFRNIHH NPDHFPCPEK FDPSRFEVAP KPNTFMPFGN GTHSCPGNEL 430 440 450 460 470 AKLEMLVLFH HLATKYRWST SKSESGVQFG PFALPLNGLP MSFTRKNTEQ E

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization of genes encoding ABA 8'-hydroxylase in ethylene-induced stem growth of deepwater rice (Oryza sativa L.)." Yang S.-H., Choi D. Biochem. Biophys. Res. Commun. 350:685-690(2006) [PubMed: 17022939] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, INDUCTION. Strain: cv. Pin Gaew 56.
[2]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. 93-11.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ887714 mRNA. Translation: ABI64254.1. CM000127 Genomic DNA. Translation: EAY87204.1.
3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR001128. Cyt_P450. IPR002401. Cyt_P450_E_grp-I. [Graphical view]
Gene3D	G3DSA:1.10.630.10. Cyt_P450. 1 hit.
PANTHER	PTHR19383. Cyt_P450. 1 hit.
Pfam	PF00067. p450. 1 hit. [Graphical view]
PRINTS	PR00463. EP450I. PR00385. P450.
PROSITE	PS00086. CYTOCHROME_P450. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABAH1_ORYSI

Accession

Primary (citable) accession number: Q09J79

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	October 17, 2006
Last modified:	November 25, 2008
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)