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Protein

Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic

Gene

accD

Organism
Platanus occidentalis (Sycamore) (American plane tree)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.UniRule annotation

Catalytic activityi

[Biotin carboxyl-carrier protein]-N6-carboxybiotinyl-L-lysine + acetyl-CoA = [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine + malonyl-CoA.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Pathwayi: malonyl-CoA biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes malonyl-CoA from acetyl-CoA.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic (accD)
This subpathway is part of the pathway malonyl-CoA biosynthesis, which is itself part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes malonyl-CoA from acetyl-CoA, the pathway malonyl-CoA biosynthesis and in Lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi234ZincUniRule annotation1
Metal bindingi237ZincUniRule annotation1
Metal bindingi253ZincUniRule annotation1
Metal bindingi256ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri234 – 256C4-typeUniRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processFatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00655; UER00711

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplasticUniRule annotation (EC:2.1.3.15UniRule annotation)
Short name:
ACCase subunit betaUniRule annotation
Short name:
Acetyl-CoA carboxylase carboxyltransferase subunit betaUniRule annotation
Gene namesi
Name:accDUniRule annotation
Encoded oniPlastid; Chloroplast
OrganismiPlatanus occidentalis (Sycamore) (American plane tree)
Taxonomic identifieri4403 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsProtealesPlatanaceaePlatanus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003591621 – 497Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplasticAdd BLAST497

Interactioni

Subunit structurei

Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).By similarity

Structurei

3D structure databases

ProteinModelPortaliQ09G37
SMRiQ09G37
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini230 – 497CoA carboxyltransferase N-terminalPROSITE-ProRule annotationAdd BLAST268

Sequence similaritiesi

Belongs to the AccD/PCCB family.UniRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri234 – 256C4-typeUniRule annotationAdd BLAST23

Keywords - Domaini

Zinc-finger

Family and domain databases

HAMAPiMF_01395 AcetylCoA_CT_beta, 1 hit
InterProiView protein in InterPro
IPR034733 AcCoA_carboxyl
IPR000438 Acetyl_CoA_COase_Trfase_b_su
IPR029045 ClpP/crotonase-like_dom_sf
IPR011762 COA_CT_N
PfamiView protein in Pfam
PF01039 Carboxyl_trans, 1 hit
PRINTSiPR01070 ACCCTRFRASEB
SUPFAMiSSF52096 SSF52096, 1 hit
TIGRFAMsiTIGR00515 accD, 1 hit
PROSITEiView protein in PROSITE
PS50980 COA_CT_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q09G37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKWWFNSML SNEELEHRCG LSKSMDSLGA IGNSSGSEDP VINDTDKNIH
60 70 80 90 100
SWSDIDSSSY SNVDHLFGVR NIRNFISDDT FLVRDRTGDS YSIYLDIENE
110 120 130 140 150
IFEIDNDRSF LSELESYFSS YLNNRSKSDT HYYDRYMYDT KYTWNNHINS
160 170 180 190 200
CIDSYIRSEI SIDSYISSGS DNYDNYSDSY ISSYICSESV INSSDSGSYS
210 220 230 240 250
IRTSTSTNGS DFNIRGRYND LDINKKYRHL WIQCENCYGL NYKKFFRSKM
260 270 280 290 300
NICEQCGYHL KMSSSDRIEL SIDPGTWDPM DEDMVSIDPI EFHSEEEPYK
310 320 330 340 350
DRIDSYQRKT GLTEAVQTGI GQLNGIPIAI GVMDFQFMGG SMGSVVGEKI
360 370 380 390 400
TRLIEYATNG SLPLIIVCAS GGARMQEGSL SLMQMAKISS ASYDYQSNKK
410 420 430 440 450
LFYVSILTSP TTGGVTASFG MLGDIIIAEP NAYIAFAGKR VIEQTLNKTV
460 470 480 490
PEGSQAAEYS FHKGLFDSIV PRNLLKGVLS ELFQLHGFFP LNQNSIK
Length:497
Mass (Da):56,180
Last modified:October 17, 2006 - v1
Checksum:iF1E7B5D932B4456F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ923116 Genomic DNA Translation: ABI49787.1
RefSeqiYP_740574.1, NC_008335.1

Genome annotation databases

GeneIDi4271299

Similar proteinsi

Entry informationi

Entry nameiACCD_PLAOC
AccessioniPrimary (citable) accession number: Q09G37
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: October 17, 2006
Last modified: May 23, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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