Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chromatin structure-remodeling complex subunit rsc4

Gene

rsc4

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Chromatin structure-remodeling complex subunit rsc4
Alternative name(s):
Bromodomain-containing protein brd1
RSC complex subunit rsc4
Gene namesi
Name:rsc4
Synonyms:brd1
ORF Names:SPBC1734.15
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1734.15.
PomBaseiSPBC1734.15. rsc4.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleus Source: PomBase
  • RSC complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002111781 – 542Chromatin structure-remodeling complex subunit rsc4Add BLAST542

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei257Phosphoserine1 Publication1
Modified residuei271Phosphoserine1 Publication1
Modified residuei287Phosphoserine1 Publication1
Modified residuei313Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ09948.
PRIDEiQ09948.

PTM databases

iPTMnetiQ09948.

Interactioni

Subunit structurei

Component of the RSC complex composed of at least arp9, arp42, rsc1, rsc4, rsc7, rsc9, rsc58, sfh1, snf21, ssr1, ssr2, ssr3 and ssr4. The complex interacts with histone and histone variant components of centromeric chromatin (By similarity).By similarity

Protein-protein interaction databases

BioGridi276543. 136 interactors.
DIPiDIP-48391N.
MINTiMINT-4696544.

Structurei

3D structure databases

ProteinModelPortaliQ09948.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 99Bromo 1PROSITE-ProRule annotationAdd BLAST71
Domaini162 – 232Bromo 2PROSITE-ProRule annotationAdd BLAST71

Sequence similaritiesi

Contains 2 bromo domains.PROSITE-ProRule annotation

Keywords - Domaini

Bromodomain, Repeat

Phylogenomic databases

InParanoidiQ09948.
OrthoDBiEOG092C2J71.

Family and domain databases

Gene3Di1.20.920.10. 2 hits.
InterProiIPR001487. Bromodomain.
[Graphical view]
PfamiPF00439. Bromodomain. 2 hits.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 2 hits.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 2 hits.
PROSITEiPS50014. BROMODOMAIN_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09948-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDDSHNAPF DKTKFDEVLE ALVGLKDNEG NPFDDIFEEL PSKRYFPDYY
60 70 80 90 100
QIIQKPICYK MMRNKAKTGK YLSMGDFYDD IRLMVSNAQT YNMPGSLVYE
110 120 130 140 150
CSVLIANTAN SLESKDGTLN EEENEEMESS INEEHKPGTN EIDVPKVIQN
160 170 180 190 200
ILDALHEEKD EQGRFLIDIF IDLPSKRLYP DYYEIIKSPM TIKMLEKRFK
210 220 230 240 250
KGEYTTLESF VKDLNQMFIN AKTYNAPGSF VYEDAEKLSQ LSSSLISSFS
260 270 280 290 300
EQPKEHSPAT SKHEPEETPA SPTPSVSAST SRERSTSVAP SFITSDQAAT
310 320 330 340 350
PDVLKSEEAH VESFSKESEK DQTPIPEDVP SPMDTLSQAN YGAFALIKSF
360 370 380 390 400
PSTPVPDFLN FSHKSVMGRS TFNMPNFPEP KFFEDIPNTE RCILSAFICS
410 420 430 440 450
PPQLPLPNPL RMYLPCPSLN STEVSVITLA PQHSFLNIVI NLNPALALKS
460 470 480 490 500
YTIITLLNGK RLGAGVSTPP STLYALEGIK HTEEPIRTVY EAKLSVGLNC
510 520 530 540
LEFVLGSTEP VEPPSIEPGL PASAYSRTVE RERFVLMAYV QP
Length:542
Mass (Da):60,667
Last modified:November 1, 1996 - v1
Checksum:iB900D1F77327C2A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86764 Genomic DNA. Translation: CAA60444.1.
CU329671 Genomic DNA. Translation: CAA21309.1.
PIRiS58680. S54260.
RefSeqiNP_595432.1. NM_001021340.2.

Genome annotation databases

EnsemblFungiiSPBC1734.15.1; SPBC1734.15.1:pep; SPBC1734.15.
GeneIDi2539999.
KEGGispo:SPBC1734.15.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86764 Genomic DNA. Translation: CAA60444.1.
CU329671 Genomic DNA. Translation: CAA21309.1.
PIRiS58680. S54260.
RefSeqiNP_595432.1. NM_001021340.2.

3D structure databases

ProteinModelPortaliQ09948.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276543. 136 interactors.
DIPiDIP-48391N.
MINTiMINT-4696544.

PTM databases

iPTMnetiQ09948.

Proteomic databases

MaxQBiQ09948.
PRIDEiQ09948.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC1734.15.1; SPBC1734.15.1:pep; SPBC1734.15.
GeneIDi2539999.
KEGGispo:SPBC1734.15.

Organism-specific databases

EuPathDBiFungiDB:SPBC1734.15.
PomBaseiSPBC1734.15. rsc4.

Phylogenomic databases

InParanoidiQ09948.
OrthoDBiEOG092C2J71.

Miscellaneous databases

PROiQ09948.

Family and domain databases

Gene3Di1.20.920.10. 2 hits.
InterProiIPR001487. Bromodomain.
[Graphical view]
PfamiPF00439. Bromodomain. 2 hits.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 2 hits.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 2 hits.
PROSITEiPS50014. BROMODOMAIN_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRSC4_SCHPO
AccessioniPrimary (citable) accession number: Q09948
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.